Nedd4 regulates egress of Ebola virus-like particles from host cells. - Wikidata - awgldk - TriplyDB

Nedd4 regulates egress of Ebola virus-like particles from host cells.

Nedd4 regulates egress of Ebola virus-like particles from host cells.

http://www.wikidata.org/entity/Q36464448

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ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral response Inhibition of Lassa and Marburg virus production by tetherin Antigenic properties of N protein of hantavirus Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1 The multifunctional Ebola virus VP40 matrix protein is a promising therapeutic target.Dimerization of tetherin is not essential for its antiviral activity against Lassa and Marburg viruses Identification of essential filovirion-associated host factors by serial proteomic analysis and RNAi screen.VP40 octamers are essential for Ebola virus replication.Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages Ebola virus VP40 late domains are not essential for viral replication in cell culture Oligomerization of Ebola virus VP40 is essential for particle morphogenesis and regulation of viral transcription Amino acid residues in the cytoplasmic domain of the Mason-Pfizer monkey virus glycoprotein critical for its incorporation into virions.Viral and host proteins that modulate filovirus budding Therapeutics for filovirus infection: traditional approaches and progress towards in silico drug design.YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42 Full-length Ebola glycoprotein accumulates in the endoplasmic reticulum.Cellular factors required for Lassa virus budding.Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge.The VP40 protein of Marburg virus exhibits impaired budding and increased sensitivity to human tetherin following mouse adaptation Molecular mechanism of arenavirus assembly and budding.Functional characterization of the putative hepatitis B virus core protein late domain using retrovirus chimeras.Nedd4-mediated increase in HIV-1 Gag and Env proteins and immunity following DNA-vaccination of BALB/c mice Small-molecule probes targeting the viral PPxY-host Nedd4 interface block egress of a broad range of RNA viruses.Viral and cellular requirements for the budding of feline endogenous retrovirus RD-114.Role of ubiquitin in parainfluenza virus 5 particle formation.Interaction of Tsg101 with Marburg virus VP40 depends on the PPPY motif, but not the PT/SAP motif as in the case of Ebola virus, and Tsg101 plays a critical role in the budding of Marburg virus-like particles induced by VP40, NP, and GP.Regulation of HTLV-1 Gag budding by Vps4A, Vps4B, and AIP1/Alix Filovirus-like particles as vaccines and discovery tools.Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.Ubiquitin-dependent virus particle budding without viral protein ubiquitination HECT ubiquitin ligases link viral and cellular PPXY motifs to the vacuolar protein-sorting pathway.Development of treatment strategies to combat Ebola and Marburg viruses.Ebola virus matrix protein VP40 uses the COPII transport system for its intracellular transport.Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase Analysis of Assembly and Budding of Lujo Virus.Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and small ubiquitin-related modifiers.Mechanisms for enveloped virus budding: can some viruses do without an ESCRT?

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Nedd4 regulates egress of Ebola virus-like particles from host cells.

http://www.wikidata.org/entity/Q36464448

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Nedd4 regulates egress of Ebola virus-like particles from host cells.

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Nedd4 regulates egress of Ebola virus-like particles from host cells.

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type

label

Nedd4 regulates egress of Ebola virus-like particles from host cells.

@ast

Nedd4 regulates egress of Ebola virus-like particles from host cells.

@en

prefLabel

Nedd4 regulates egress of Ebola virus-like particles from host cells.

@ast

Nedd4 regulates egress of Ebola virus-like particles from host cells.

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JVI.77.18.9987-9992.2003

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Journal of Virology

P1476

Nedd4 regulates egress of Ebola virus-like particles from host cells.

@en

P2093

Hisatoshi Shida

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Jiro Yasuda

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Mitsuyoshi Nakao

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P2860

Human ubiquitin-protein ligase Nedd4: expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function

Proteins related to the Nedd4 family of ubiquitin protein ligases interact with the L domain of Rous sarcoma virus and are required for gag budding from cells

Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release

Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag)

An assembly domain of the Rous sarcoma virus Gag protein required late in budding

Structure and functional interactions of the Tsg101 UEV domain.

A PPxY motif within the VP40 protein of Ebola virus interacts physically and functionally with a ubiquitin ligase: implications for filovirus budding

HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

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9987-9992

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scholarly article

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10.1128/JVI.77.18.9987-9992.2003

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18

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77

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Yoshihiro Kawaoka

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2003-09-01T00:00:00Z

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12941909

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