MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer - Wikidata - awgldk - TriplyDB

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

http://www.wikidata.org/entity/Q36469814

about

Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1 Trial Watch: Proteasomal inhibitors for anticancer therapy A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2 Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine.Molecular pathways and targets in prostate cancer The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc.Clear cell papillary renal cell carcinoma: micro-RNA expression profiling and comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma.Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2 Deubiquitinases in cancer.Oxidative stress response and Nrf2 signaling in aging.ellipsoidFN: a tool for identifying a heterogeneous set of cancer biomarkers based on gene expressions.The interplay of long non-coding RNAs and MYC in cancer MicroRNA-449a enhances radiosensitivity by downregulation of c-Myc in prostate cancer cells MicroRNA expression and function in prostate cancer: a review of current knowledge and opportunities for discovery USP2a alters chemotherapeutic response by modulating redox.Role of ubiquitin ligases and the proteasome in oncogenesis: novel targets for anticancer therapies.The ubiquitin-specific protease USP2a prevents endocytosis-mediated EGFR degradation.Analysis of the genomic response of human prostate cancer cells to histone deacetylase inhibitors.MicroRNA-based screens for synthetic lethal interactions with c-Myc Targeting the ubiquitin-mediated proteasome degradation of p53 for cancer therapy.Roles of microRNAs during prostatic tumorigenesis and tumor progression.Deubiquitinases and the new therapeutic opportunities offered to cancer.DUBs, the regulation of cell identity and disease.Non-coding RNAs in Prostate Cancer: From Discovery to Clinical Applications.Deciphering the function of non-coding RNAs in prostate cancer.NVP-LDE-225 (Erismodegib) inhibits epithelial-mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128.Myc-dependent purine biosynthesis affects nucleolar stress and therapy response in prostate cancer.Macrophage ubiquitin-specific protease 2 modifies insulin sensitivity in obese mice.USP2a activation of MYC in prostate cancer.Fifty-Hertz Magnetic Field Affects the Epigenetic Modulation of the miR-34b/c in Neuronal Cells.Harnessing the oxidation susceptibility of deubiquitinases for inhibition with small molecules.The epigenetic component of the brain response to electromagnetic stimulation in Parkinson's Disease patients: A literature overview.Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.

P2860

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P2860

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

http://www.wikidata.org/entity/Q36469814

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

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MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

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type

label

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

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MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

@en

prefLabel

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

@ast

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

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2159-8290.CD-11-0219

P1433

Cancer Discovery

P1476

MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancer

@en

P2093

Barbara Benassi

http://www.w3.org/2001/XMLSchema#string

Dipanjan Chowdhury

http://www.w3.org/2001/XMLSchema#string

Giovanni Blandino

http://www.w3.org/2001/XMLSchema#string

Luigi Marchionni

http://www.w3.org/2001/XMLSchema#string

Marina Marani

http://www.w3.org/2001/XMLSchema#string

Paola Muti

http://www.w3.org/2001/XMLSchema#string

Richard Flavin

http://www.w3.org/2001/XMLSchema#string

Sabrina Strano

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Silvio Zanata

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Yunfeng Pan

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P2860

Prediction and preliminary validation of oncogene regulation by miRNAs

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2

The ubiquitin-specific protease USP28 is required for MYC stability

Suppression of cancer cell growth by promoting cyclin D1 degradation

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

A microRNA expression signature of human solid tumors defines cancer gene targets

p53 represses c-Myc through induction of the tumor suppressor miR-145

Widespread microRNA repression by Myc contributes to tumorigenesis

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236-247

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scholarly article

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10.1158/2159-8290.CD-11-0219

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3

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2

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