Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay
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Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decayA competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decayUnusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exonNonsense-mediated mRNA decay: novel mechanistic insights and biological impactThe role of mammalian poly(A)-binding proteins in co-ordinating mRNA turnoverGene expression regulation by upstream open reading frames and human diseaseNonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryMosaic PPM1D mutations are associated with predisposition to breast and ovarian cancerEukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanismsHigh-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE.Nucleosome deposition and DNA methylation may participate in the recognition of premature termination codon in nonsense-mediated mRNA decay.Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay.Nonsense-mediated RNA decay regulation by cellular stress: implications for tumorigenesis.Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombeIs there a classical nonsense-mediated decay pathway in trypanosomes?A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.When a ribosome encounters a premature termination codon.Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels.The regulation of mRNA stability in mammalian cells: 2.0.Unspliced precursors of NMD-sensitive β-globin transcripts exhibit decreased steady-state levels in erythroid cellsOhtahara syndrome in a family with an ARX protein truncation mutation (c.81C>G/p.Y27X).The CFTR frameshift mutation 3905insT and its effect at transcript and protein level.Poly(A) binding proteins: are they all created equal?The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay.Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.Poly(A) RNA-binding proteins and polyadenosine RNA: new members and novel functions.Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.Estrogen receptor β exon 3-deleted mouse: The importance of non-ERE pathways in ERβ signalingNMD: At the crossroads between translation termination and ribosome recycling.Testing the faux-UTR model for NMD: analysis of Upf1p and Pab1p competition for binding to eRF3/Sup35p.Evidence that the Upf1-related molecular motor scans the 3'-UTR to ensure mRNA integrity.The role of nucleotide composition in premature termination codon recognition.Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase ActivityIdentification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability.Regulation of nonsense-mediated mRNA decay: implications for physiology and disease.DMD exon 1 truncating point mutations: amelioration of phenotype by alternative translation initiation in exon 6.Posttranscriptional gene regulation by spatial rearrangement of the 3' untranslated region.Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways
P2860
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P2860
Proximity of the poly(A)-binding protein to a premature termination codon inhibits mammalian nonsense-mediated mRNA decay
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2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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name
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@ast
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@en
type
label
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@ast
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@en
prefLabel
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@ast
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@en
P2093
P2860
P50
P356
P1433
P1476
Proximity of the poly(A)-bindi ...... n nonsense-mediated mRNA decay
@en
P2093
Ana Luísa Silva
Angela Inácio
Luísa Romão
Patrícia Ribeiro
Stephen A Liebhaber
P2860
P304
P356
10.1261/RNA.815108
P407
P577
2008-01-29T00:00:00Z