Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability. - Wikidata - awgldk - TriplyDB

Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability.

Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability.

http://www.wikidata.org/entity/Q36684609

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The RNA degradation pathway regulates the function of GAS5 a non-coding RNA in mammalian cells DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact Mechanism and regulation of the nonsense-mediated decay pathway Nonsense-mediated mRNA decay: inter-individual variability and human disease Nonsense-mediated mRNA decay in humans at a glance Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanisms RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.A post-translational regulatory switch on UPF1 controls targeted mRNA degradation The interaction of cytoplasmic poly(A)-binding protein with eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay.Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins.Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells.Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance.Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics.Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.Increased expression of X-linked genes in mammals is associated with a higher stability of transcripts and an increased ribosome density.Nonsense-mediated RNA decay--a switch and dial for regulating gene expression UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.The role of nucleotide composition in premature termination codon recognition.Recent transcriptome-wide mapping of UPF1 binding sites reveals evidence for its recruitment to mRNA before translation.Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability.Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila.Role of SMG-1-mediated Upf1 phosphorylation in mammalian nonsense-mediated mRNA decay.Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs.Nonsense suppression therapies in ocular genetic diseases.Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers.Physiological and pathophysiological role of nonsense-mediated mRNA decay.A GC-rich sequence feature in the 3' UTR directs UPF1-dependent mRNA decay in mammalian cells.Stress and the nonsense-mediated RNA decay pathway.Control of gene expression through the nonsense-mediated RNA decay pathway.The rules and impact of nonsense-mediated mRNA decay in human cancers.Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay.Assessing the activity of nonsense-mediated mRNA decay in lung cancer.Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay.Inhibition of nonsense-mediated RNA decay by ER stress.

P2860

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P2860

Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability.

http://www.wikidata.org/entity/Q36684609

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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name

Identification of hundreds of ...... whole transcriptome stability.

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Identification of hundreds of ...... whole transcriptome stability.

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Identification of hundreds of ...... whole transcriptome stability.

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Identification of hundreds of ...... whole transcriptome stability.

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Identification of hundreds of ...... whole transcriptome stability.

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Identification of hundreds of ...... whole transcriptome stability.

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Identification of hundreds of ...... whole transcriptome stability.

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Kazi Abdus Salam

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Kenichi Ijiri

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Nobuyoshi Akimitsu

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Rena Mizutani

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Takuma Irie

http://www.w3.org/2001/XMLSchema#string

Tetsushi Yada

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Yutaka Suzuki

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P2860

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif.

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways

Mammalian orthologues of a yeast regulator of nonsense transcript stability

Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

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1370-1379

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10.4161/RNA.22360

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11

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9

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