Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
about
Therapeutic rescue of misfolded mutants: validation of primary high throughput screens for identification of pharmacoperone drugsPharmacoperone Identification for Therapeutic Rescue of Misfolded Mutant ProteinsStructural and mechanistic insight into the basis of mucopolysaccharidosis IIIBA multiparametric computational algorithm for comprehensive assessment of genetic mutations in mucopolysaccharidosis type IIIA (Sanfilippo syndrome)Trafficking and quality control of the gonadotropin releasing hormone receptor in health and diseaseA phenotypic high throughput screening assay for the identification of pharmacoperones for the gonadotropin releasing hormone receptorTransitioning pharmacoperones to therapeutic use: in vivo proof-of-principle and design of high throughput screens.Chaperoning G protein-coupled receptors: from cell biology to therapeuticsConstrained bithiazoles: small molecule correctors of defective ΔF508-CFTR protein trafficking.Pharmacological chaperones for misfolded gonadotropin-releasing hormone receptorsAssay strategies for identification of therapeutic leads that target protein traffickingExpanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines.FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stabilityNeuronal signaling modulates protein homeostasis in Caenorhabditis elegans post-synaptic muscle cells.A functional null mutation of SCN1B in a patient with Dravet syndrome.Chemical chaperone and inhibitor discovery: potential treatments for protein conformational diseases.Knitting and untying the protein network: modulation of protein ensembles as a therapeutic strategy.Alternate strategies of Hsp90 modulation for the treatment of cancer and other diseases.Misfolded proteins and neurodegeneration: role of non-native cytochrome c in cell death.Pharmacological chaperone therapy for Gaucher disease: a patent review.Matrine modulates HSC70 levels and rescues ΔF508-CFTR.Biochemical and biophysical approaches to probe CFTR structure.Grand challenge for ion channels: an underexploited resource for therapeutics.What are pharmacological chaperones and why are they interesting?A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.
P2860
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P2860
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@ast
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@en
type
label
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@ast
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@en
prefLabel
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@ast
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@en
P2860
P1476
Therapy through chaperones: sense or antisense? Cystic fibrosis as a model disease.
@en
P2093
Margarida D Amaral
P2860
P2888
P304
P356
10.1007/S10545-006-0251-X
P577
2006-04-01T00:00:00Z