Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
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The effect of ABCB1 polymorphisms on the outcome of breast cancer treatmentInsights into Chemoresistance of Prostate CancerExploiting nanotechnology to overcome tumor drug resistance: Challenges and opportunitiesIdentification and localization of a putative ATP-binding cassette transporter in sea lice (Lepeophtheirus salmonis) and host Atlantic salmon (Salmo salar)ABCB1 1199G>A genetic polymorphism (Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell linesMembrane transporters in drug developmentPolymorphism in multidrug resistance-associated protein gene 3 is associated with outcomes in childhood acute lymphoblastic leukemia.Predictive computational models of substrate binding by a nucleoside transporter.Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancerCandidate Gene Association Studies of Anthracycline-induced Cardiotoxicity: A Systematic Review and Meta-analysis.ABCB1 genetic variants in leukemias: current insights into treatment outcomesRecent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapiesUpregulation of microRNA-143 reverses drug resistance in human breast cancer cells via inhibition of cytokine-induced apoptosis inhibitor 1CIAPIN1 gene silencing enhances chemosensitivity in a drug-resistant animal model in vivo.NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.A Phase I Study of Oral Paclitaxel with a Novel P-Glycoprotein Inhibitor, HM30181A, in Patients with Advanced Solid CancerGenetic variation in drug transporters in ethnic populations.Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.Pharmacogenetics of OATP (SLC21/SLCO), OAT and OCT (SLC22) and PEPT (SLC15) transporters in the intestine, liver and kidney.Rapid detection of ABC transporter interaction: potential utility in pharmacology.ABC transporters: unvalidated therapeutic targets in cancer and the CNSSnapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings.Genetic Variations of Drug Transporters Can Influence on Drug Response in Patients Treated with Docetaxel ChemotherapyInterindividual differences in phytochemical metabolism and dispositionInhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats.Gene polymorphisms of ABC transporters are associated with clinical outcomes in children with acute lymphoblastic leukemia.ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients.In vitro and in vivo downregulation of the ATP binding cassette transporter B1 by the HMG-CoA reductase inhibitor simvastatinPlacental transfer of maraviroc in an ex vivo human cotyledon perfusion model and influence of ABC transporter expression.Pharmacogenetics of opioids.Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletionFunctional analysis of nonsynonymous single nucleotide polymorphisms of multidrug resistance-associated protein 2 (ABCC2).Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies.Transporter-mediated uptake into cellular compartments.Association of the ABCG2 C421A polymorphism with prostate cancer risk and survival.Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges.Genetic and molecular changes in ovarian cancer.Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents.Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.
P2860
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P2860
Role of pharmacogenetics of ATP-binding cassette transporters in the pharmacokinetics of drugs.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs.
@ast
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs.
@en
type
label
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs.
@ast
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs.
@en
prefLabel
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs.
@ast
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs.
@en
P1476
Role of pharmacogenetics of AT ...... the pharmacokinetics of drugs
@en
P2093
Ingolf Cascorbi
P304
P356
10.1016/J.PHARMTHERA.2006.04.009
P577
2006-11-01T00:00:00Z