Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
about
Insights into bombesin receptors and ligands: Highlighting recent advancesDiscovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.Bombesin receptor subtype 3 as a potential target for obesity and diabetes.Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss.Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells.Pharmacology of putative selective hBRS-3 receptor agonists for human bombesin receptors (BnR): affinities, potencies and selectivity in multiple native and BnR transfected cells.Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes.Integration of body temperature into the analysis of energy expenditure in the mouseSearch for an Endogenous Bombesin-Like Receptor 3 (BRS-3) Ligand Using Parabiotic MiceModular genetic control of sexually dimorphic behaviors.Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanismComparative pharmacology of bombesin receptor subtype-3, nonpeptide agonist MK-5046, a universal peptide agonist, and peptide antagonist Bantag-1 for human bombesin receptorsRegulation of body temperature and brown adipose tissue thermogenesis by bombesin receptor subtype-3.The effects of food components on hormonal signalling in gastrointestinal enteroendocrine cells.Substituted oxadiazoles: a patent review (2010 - 2012).A selective human bombesin receptor subtype-3 peptide agonist mediates CREB phosphorylation and transactivation.Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.Bombesin-Like Receptor 3: Physiology of a Functional Orphan.Pharmacokinetics and pharmacodynamics of MK-5046, a bombesin receptor subtype-3 (BRS-3) agonist, in healthy patientsBody temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments.Anatomical characterization of bombesin receptor subtype-3 mRNA expression in the rodent central nervous system.Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism.Receptor-specific crosstalk between prostanoid E receptor 3 and bombesin receptor subtype 3.Bombesin receptor subtype-3-expressing neurons regulate energy homeostasis through a novel neuronal pathway in the hypothalamus.Brs3 neurons in the mouse dorsomedial hypothalamus regulate body temperature, energy expenditure, and heart rate, but not food intake
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P2860
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
description
2007 nî lūn-bûn
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2007年の論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年論文
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2007年论文
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2007年论文
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2007年论文
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name
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@ast
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@en
type
label
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@ast
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@en
prefLabel
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@ast
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@en
P2093
P2860
P356
P1433
P1476
Factors contributing to obesity in bombesin receptor subtype-3-deficient mice
@en
P2093
Ellen E Ladenheim
James F Battey
Lori L Hampton
Nahketah L Hamilton
Robert R Behles
Timothy H Moran
P2860
P304
P356
10.1210/EN.2007-1319
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P577
2007-11-26T00:00:00Z