Factors contributing to obesity in bombesin receptor subtype-3-deficient mice - Wikidata - awgldk - TriplyDB

Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

http://www.wikidata.org/entity/Q36509779

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Insights into bombesin receptors and ligands: Highlighting recent advances Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.Bombesin receptor subtype 3 as a potential target for obesity and diabetes.Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss.Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells.Pharmacology of putative selective hBRS-3 receptor agonists for human bombesin receptors (BnR): affinities, potencies and selectivity in multiple native and BnR transfected cells.Effect of bombesin receptor subtype-3 and its synthetic agonist on signaling, glucose transport and metabolism in myocytes from patients with obesity and type 2 diabetes.Integration of body temperature into the analysis of energy expenditure in the mouse Search for an Endogenous Bombesin-Like Receptor 3 (BRS-3) Ligand Using Parabiotic Mice Modular genetic control of sexually dimorphic behaviors.Bombesin-like receptor 3 regulates blood pressure and heart rate via a central sympathetic mechanism Comparative pharmacology of bombesin receptor subtype-3, nonpeptide agonist MK-5046, a universal peptide agonist, and peptide antagonist Bantag-1 for human bombesin receptors Regulation of body temperature and brown adipose tissue thermogenesis by bombesin receptor subtype-3.The effects of food components on hormonal signalling in gastrointestinal enteroendocrine cells.Substituted oxadiazoles: a patent review (2010 - 2012).A selective human bombesin receptor subtype-3 peptide agonist mediates CREB phosphorylation and transactivation.Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.Bombesin-Like Receptor 3: Physiology of a Functional Orphan.Pharmacokinetics and pharmacodynamics of MK-5046, a bombesin receptor subtype-3 (BRS-3) agonist, in healthy patients Body temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments.Anatomical characterization of bombesin receptor subtype-3 mRNA expression in the rodent central nervous system.Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism.Receptor-specific crosstalk between prostanoid E receptor 3 and bombesin receptor subtype 3.Bombesin receptor subtype-3-expressing neurons regulate energy homeostasis through a novel neuronal pathway in the hypothalamus.Brs3 neurons in the mouse dorsomedial hypothalamus regulate body temperature, energy expenditure, and heart rate, but not food intake

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Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

http://www.wikidata.org/entity/Q36509779

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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type

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Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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prefLabel

Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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Factors contributing to obesity in bombesin receptor subtype-3-deficient mice

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Ellen E Ladenheim

http://www.w3.org/2001/XMLSchema#string

James F Battey

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Lori L Hampton

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Nahketah L Hamilton

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Robert R Behles

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Sheng Bi

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Timothy H Moran

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P2860

Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity

BRS-3: a novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells

The distribution of the orphan bombesin receptor subtype-3 in the rat CNS

Molecular cloning of the bombesin/gastrin-releasing peptide receptor from Swiss 3T3 cells

Central nervous system control of food intake

Bombesin-like peptides: studies on food intake and social behaviour with receptor knock-out mice.

Molecular basis of the pharmacological difference between rat and human bombesin receptor subtype-3 (BRS-3).

Organization and chromosomal localization of the gene for the human bombesin receptor subtype expressed in pregnant uterus.

Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology compared with other mammalian bombesin receptors.

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971-978

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10.1210/EN.2007-1319

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18039774

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