Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets - Wikidata - awgldk - TriplyDB

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

http://www.wikidata.org/entity/Q36532167

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Recruitment and activation of SHP-1 protein-tyrosine phosphatase by human platelet endothelial cell adhesion molecule-1 (PECAM-1). Identification of immunoreceptor tyrosine-based inhibitory motif-like binding motifs and substrates Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly Translocation of the Csk homologous kinase (Chk/Hyl) controls activity of CD36-anchored Lyn tyrosine kinase in thrombin-stimulated platelets Site-specific phosphorylation of platelet focal adhesion kinase by low-density lipoprotein Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity Rho-stimulated contractility drives the formation of stress fibers and focal adhesions Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrins Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase Signal transduction from the extracellular matrix PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation Phosphatidylinositol 3,4,5-trisphosphate directs association of Src homology 2-containing signaling proteins with gelsolin Primary arrest of circulating platelets on collagen involves phosphorylation of Syk, cortactin and focal adhesion kinase: studies under flow conditions The hunting of the Src Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion Phosphorylation of focal adhesion vasodilator-stimulated phosphoprotein at Ser157 in intact human platelets correlates with fibrinogen receptor inhibition Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1)Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2 Relocation of Syk protein-tyrosine kinase to the actin filament network and subsequent association with Fak Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin Cytoskeletal integrity is required throughout the mitogen stimulation phase of the cell cycle and mediates the anchorage-dependent expression of cyclin D1 Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src)Identification of an interaction between the m-band protein skelemin and beta-integrin subunits. Colocalization of a skelemin-like protein with beta1- and beta3-integrins in non-muscle cells Interaction of focal adhesion kinase with cytoskeletal protein talin The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas

P2860

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P2860

Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets

http://www.wikidata.org/entity/Q36532167

description

1992 nî lūn-bûn

@nan

1992年の論文

@ja

1992年論文

@yue

1992年論文

@zh-hant

1992年論文

@zh-hk

1992年論文

@zh-mo

1992年論文

@zh-tw

1992年论文

@wuu

1992年论文

@zh

1992年论文

@zh-cn

name

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@ast

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@en

type

label

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@ast

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@en

prefLabel

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@ast

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@en

P1433

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P1433

Journal of Cell Biology

P1476

Integrin-dependent phosphoryla ...... e kinase pp125FAK in platelets

@en

P2093

B Haimovich

http://www.w3.org/2001/XMLSchema#string

B S Cobb

http://www.w3.org/2001/XMLSchema#string

J S Brugge

http://www.w3.org/2001/XMLSchema#string

J T Parsons

http://www.w3.org/2001/XMLSchema#string

L Lipfert

http://www.w3.org/2001/XMLSchema#string

M D Schaller

http://www.w3.org/2001/XMLSchema#string

P2860

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Integrins: versatility, modulation, and signaling in cell adhesion

Exposure of platelet fibrinogen receptors by ADP and epinephrine.

Tyrosine-specific protein phosphorylation is regulated by glycoprotein IIb-IIIa in platelets.

Reorganization of actin in platelets stimulated by thrombin as measured by the DNase I inhibition assay.

Activation of phospholipases A and C in human platelets exposed to epinephrine: role of glycoproteins IIb/IIIa and dual role of epinephrine.

Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb-IIIa complex at high shear rate.

Role of platelet membrane glycoprotein IIb-IIIa in agonist-induced tyrosine phosphorylation of platelet proteins.

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons.

P304

905-912

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scholarly article

P356

10.1083/JCB.119.4.905

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P433

4

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119

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1992-11-01T00:00:00Z

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277417569

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P698

1385445

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P921

phosphorylation

P932

2289696

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