about
Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorumEsterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infectionInhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilonThe 1.85 Å Structure of an 8 R -Lipoxygenase Suggests a General Model for Lipoxygenase Product SpecificityPotential Antifungal Targets against a Candida Biofilm Based on an Enzyme in the Arachidonic Acid Cascade-A ReviewBoswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical dataGenetics and pharmacogenetics of the leukotriene pathwayRecent advances in the search for novel 5-lipoxygenase inhibitorsDiscovery of a novel dual fungal CYP51/human 5-lipoxygenase inhibitor: implications for anti-fungal therapyMethyl jasmonate: putative mechanisms of action on cancer cells cycle, metabolism, and apoptosisElectrophilic fatty acid species inhibit 5-lipoxygenase and attenuate sepsis-induced pulmonary inflammation.Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrateTrihydroxyflavones with antioxidant and anti-inflammatory efficacy.Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.Urinary LTE4 levels as a diagnostic marker for IgE-mediated asthma in preschool children: a birth cohort study.Caulerpenyne and related bis-enol esters are novel-type inhibitors of human 5-lipoxygenase.Resolvins and protectins in inflammation resolution.MK591, a second generation leukotriene biosynthesis inhibitor, prevents invasion and induces apoptosis in the bone-invading C4-2B human prostate cancer cells: implications for the treatment of castration-resistant, bone-metastatic prostate cancer.Chromones: A Promising Ring System for New Anti-inflammatory Drugs.Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization.The Protective Effect of Eupatilin against Hydrogen Peroxide-Induced Injury Involving 5-Lipoxygenase in Feline Esophageal Epithelial Cells.Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase.Improving protein crystal quality by selective removal of a Ca(2+)-dependent membrane-insertion loop5-Lipoxygenase: mechanisms of regulation.The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cellsA Novel Inhibitor of 5-Lipoxygenase (5-LOX) Prevents Oxidative Stress-Induced Cell Death of Retinal Pigment Epithelium (RPE) CellsMicrosomal prostaglandin E synthase 1 determines tumor growth in vivo of prostate and lung cancer cells5-Lipoxygenase inhibitors: a review of recent developments and patents.Baicalin attenuates oxygen-glucose deprivation-induced injury by inhibiting oxidative stress-mediated 5-lipoxygenase activation in PC12 cells.5-Lipoxygenase inhibitors: a review of recent patents (2010-2012).Potency of non-steroidal anti-inflammatory drugs in chemotherapy.Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells.Lipoxygenase directed anti-inflammatory and anti-cancerous secondary metabolites: ADMET-based screening, molecular docking and dynamics simulation.The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.Structure-activity relationship and in vitro pharmacological evaluation of imidazo[1,2-a]pyridine-based inhibitors of 5-LO.The discovery of setileuton, a potent and selective 5-lipoxygenase inhibitor.5-Lipoxygenase inhibitors induce potent anti-proliferative and cytotoxic effects in human tumour cells independently of suppression of 5-lipoxygenase activity.Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense.Dual-target virtual screening by pharmacophore elucidation and molecular shape filtering.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Therapeutic options for 5-lipoxygenase inhibitors.
@ast
Therapeutic options for 5-lipoxygenase inhibitors.
@en
type
label
Therapeutic options for 5-lipoxygenase inhibitors.
@ast
Therapeutic options for 5-lipoxygenase inhibitors.
@en
prefLabel
Therapeutic options for 5-lipoxygenase inhibitors.
@ast
Therapeutic options for 5-lipoxygenase inhibitors.
@en
P1476
Therapeutic options for 5-lipoxygenase inhibitors.
@en
P304
P356
10.1016/J.PHARMTHERA.2006.05.009
P577
2006-07-11T00:00:00Z