Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
about
Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNAHuman homeobox HOXA7 regulates keratinocyte transglutaminase type 1 and inhibits differentiationStructural determinants within Pbx1 that mediate cooperative DNA binding with pentapeptide-containing Hox proteins: proposal for a model of a Pbx1-Hox-DNA complexPrep1, a novel functional partner of Pbx proteins.The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativityPBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteinsTrimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activityAbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteinsMeis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1Critical role for a single leucine residue in leukemia induction by E2A-PBX1Lock and key binding of the HOX YPWM peptide to the PBX homeodomainThe homeodomain proteins PBX and MEIS1 are accessory factors that enhance thyroid hormone regulation of the malic enzyme gene in hepatocytesHOXB13 homeodomain protein is cytoplasmic throughout fetal skin developmentA conserved C-terminal domain in PBX increases DNA binding by the PBX homeodomain and is not a primary site of contact for the YPWM motif of HOXA1Functional dissection of the mouse Hox-a5 geneRepression by HoxA7 is mediated by the homeodomain and the modulatory action of its N-terminal-arm residuesMeis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteinsChanges in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiationAn Abd-B class HOX.PBX recognition sequence is required for expression from the mouse Ren-1c gene.Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1.TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1.Endothelial cells express a novel, tumor necrosis factor-alpha-regulated variant of HOXA9.The Abd-B-like Hox homeodomain proteins can be subdivided by the ability to form complexes with Pbx1a on a novel DNA target.Selective repression of transcriptional activators by Pbx1 does not require the homeodomainHigh incidence of proviral integrations in the Hoxa locus in a new model of E2a-PBX1-induced B-cell leukemia.The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cellsRole for homodimerization in growth deregulation by E2a fusion proteins.An Otx-related homeodomain protein binds an LHbeta promoter element important for activation during gonadotrope maturation.Hox proteins display a common and ancestral ability to diversify their interaction mode with the PBC class cofactors.The TALE homeodomain protein Pbx2 is not essential for development and long-term survivalThe role of E2A-PBX1 in leukemogenesis.Hox genes and their candidate downstream targets in the developing central nervous system.Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA.A genetic screen of the Drosophila X chromosome for mutations that modify Deformed function.HOX and non-HOX homeobox genes in leukemic hematopoiesis.Microarray Analysis of Defective Cartilage in Hoxc8- and Hoxd4-Transgenic Mice.Functional and regulatory interactions between Hox and extradenticle genes.The Homothorax homeoprotein activates the nuclear localization of another homeoprotein, extradenticle, and suppresses eye development in Drosophila.The control of trunk Hox specificity and activity by ExtradenticlePre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth.
P2860
Q22254126-282105E1-B48B-4DE8-A9B2-EA34A8EB6A00Q24291398-5EC82ECA-CA71-4B50-BB05-9323F3C77B44Q24317529-3C3C2CAA-F484-49C4-8189-8579831550ABQ24533175-C01DFE5D-B67A-456D-9694-8534A6319FD4Q24533177-86FDACF6-8D6A-4A2D-AE20-B9192E363BF8Q24554397-E103C6EE-0279-49C3-9422-F875E326FCB8Q24554470-BD06E8CE-7158-4C60-9B36-D2DB1BBAEAE4Q24644374-14EEEB72-AECB-4F39-9839-7FD1F906D582Q24646482-7932863E-90F0-4D58-948E-43AE139CBB73Q24670517-DC14F3B9-48C3-40CE-A9B8-E4D84AF76C0EQ27639896-1BB2B861-4D03-4B81-8CD5-DC955A2366B0Q28186611-C86948EE-D10B-45F1-A5E0-1DDF488A24B6Q28205957-5D459062-0245-4CDE-9C3F-E0F0C98419DAQ28270511-8AE027FC-9FF4-47D5-AF53-9799404D0EA6Q28585623-89C3C400-936A-43FD-BA2A-CE6DD85F6758Q28586979-2A7C6410-9D90-4329-BDF9-EB35A5B31B6DQ28588001-D88092B5-4BDB-414F-9B2C-7112D9E21E7BQ29042297-091434DD-E06E-4A78-93E2-473CA72A7015Q30176402-B278EA6B-8D8F-4DAB-9423-46247B5B670DQ30496250-0F9BE3E6-4277-47EC-B634-C9CB66B49BD4Q31060443-E5C7690E-9D6B-4C59-A97F-7678FA31CA49Q31938043-3BC52D47-BC52-48BD-B01D-AEB92B5DC05CQ32874802-8F7B0DD5-BEB9-45CB-9AE0-15FDD2F0156FQ33631085-A35FECA8-F90A-4E72-A3D7-AF9FBCED4603Q33763739-F955D182-E049-4BD3-B14D-B671D9CC7D9AQ33959545-F3F8558F-6681-4B75-89C1-E20FD5E38DBEQ33964971-F6237280-A9A4-4967-97E2-E9E3B437BAB1Q34099931-F421E6ED-B3D2-47BB-8212-C51FB59E2FE6Q34321007-CEBCE13E-6995-4EA8-88EF-C4B79B87883FQ34347200-BC5AA9B9-A43B-4CD7-B5F8-4650897707E6Q34405471-23B3DC00-F339-4E9E-959D-4FB3FCF38BD4Q34439668-514D68E6-D241-4EDC-991F-A20A65C5C0BBQ34591843-7F0CB40F-40FE-4A92-9600-4332CF527571Q34605862-FD6306F1-11EA-4ACB-9254-46719EFC0AFCQ34915527-974FC243-51A3-4D53-B792-517D612A92C5Q34977920-80EF22A2-C4B7-48FB-84EF-8310014C4ABBQ35188306-CB0426F5-3C0C-4020-A43A-405C509E7A73Q35189991-8491D8B7-354D-45F0-B275-DABA9B8A6436Q35200880-2E36E3CA-139E-4BEC-85A6-F6DC4E37CA4EQ35570348-3CAC9FC2-AB91-4B4A-9642-E44E06321960
P2860
Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Both Pbx1 and E2A-Pbx1 bind th ...... hich are themselves oncogenes.
@ast
Both Pbx1 and E2A-Pbx1 bind th ...... hich are themselves oncogenes.
@en
type
label
Both Pbx1 and E2A-Pbx1 bind th ...... hich are themselves oncogenes.
@ast
Both Pbx1 and E2A-Pbx1 bind th ...... hich are themselves oncogenes.
@en
prefLabel
Both Pbx1 and E2A-Pbx1 bind th ...... hich are themselves oncogenes.
@ast
Both Pbx1 and E2A-Pbx1 bind th ...... hich are themselves oncogenes.
@en
P2093
P2860
P356
P1476
Both Pbx1 and E2A-Pbx1 bind th ...... which are themselves oncogenes
@en
P2093
P2860
P304
P356
10.1128/MCB.15.7.3786
P407
P577
1995-07-01T00:00:00Z