Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease.
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Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared MechanismsAlzheimer's pathogenesis and its link to the mitochondrionEarly etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?Curcumin and Resveratrol in the Management of Cognitive Disorders: What is the Clinical Evidence?Three dimensions of the amyloid hypothesis: time, space and 'wingmen'Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid betaPathogenic PS1 phosphorylation at Ser367Convergence of pathology in dementia with Lewy bodies and Alzheimer's disease: a role for the novel interaction of alpha-synuclein and presenilin 1 in disease.The dynamic conformational landscape of gamma-secretase.Oxidative stress and lipid peroxidation are upstream of amyloid pathology.Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis.Interrelationship between changes in the amyloid β 42/40 ratio and presenilin 1 conformationDynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.Deconstructing mitochondrial dysfunction in Alzheimer disease.The role of s-nitrosylation and s-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration.Neuronal Ryanodine Receptors in Development and Aging.Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer's Disease Pathogenesis.A Translational Systems Pharmacology Model for Aβ Kinetics in Mouse, Monkey, and Human.Studying the Progression of Amyloid Pathology and Its Therapy Using Translational Longitudinal Model of Accumulation and Distribution of Amyloid Beta.Perspective Insights into Disease Progression, Diagnostics, and Therapeutic Approaches in Alzheimer's Disease: A Judicious Update.The Presenilin loop region is essential for Glycogen synthase kinase 3 beta mediated functions on motor proteins during axonal transport.Novel interaction between Alzheimer's disease-related protein presenilin 1 and glutamate transporter 1.
P2860
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P2860
Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@ast
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@en
type
label
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@ast
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@en
prefLabel
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@ast
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@en
P2093
P2860
P50
P1476
Presenilin-1 adopts pathogenic ...... sporadic Alzheimer's disease.
@en
P2093
Kathryn Leigh Post
Kengo Uemura
Navine Nasser-Ghodsi
Oksana Berezovska
P2860
P2888
P304
P356
10.1007/S00401-012-1065-6
P577
2012-11-09T00:00:00Z