Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
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Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism.The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperoneBurkitt's lymphoma: new insights into molecular pathogenesisDisruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein bindingIdentification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture modelPlakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasisIC-tagging and protein relocation to ARV muNS inclusions: a method to study protein-protein interactions in the cytoplasm or nucleus of living cellsCrk and CrkL are required for cell transformation by v-fos and v-ras.p53 targets simian virus 40 large T antigen for acetylation by CBPThe SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.Developmental defects and tumor predisposition in Rb mutant mice.The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins.Simian virus 40 large T antigen stabilizes the TATA-binding protein-TFIIA complex on the TATA element.Activation of RNA polymerase III transcription in cells transformed by simian virus 40The retinoblastoma protein is linked to the activation of Ras.Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells.Enumeration of the simian virus 40 early region elements necessary for human cell transformationThe DNA damage response in viral-induced cellular transformationThe B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylationT antigens of simian virus 40: molecular chaperones for viral replication and tumorigenesisOverexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators.Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts.Uroplakins in urothelial biology, function, and diseaseCellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Regulation of endogenous E2F1 stability by the retinoblastoma family proteins.PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A.Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization.Simian virus 40 large T antigen alters the phosphorylation state of the RB-related proteins p130 and p107.Enterocyte proliferation and intestinal hyperplasia induced by simian virus 40 T antigen require a functional J domainSkeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.Immortalized cells as experimental models to study cancer.Expression of the small T antigen of Lymphotropic Papovavirus is sufficient to transform primary mouse embryo fibroblasts.Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.Nuclear factor of activated T-cells (NFAT) plays a role in SV40 infection.Interaction between simian virus 40 large T antigen and insulin receptor substrate 1 is disrupted by the K1 mutation, resulting in the loss of large T antigen-mediated phosphorylation of Akt.Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen.Different Roles of Negative and Positive Components of the Circadian Clock in Oncogene-induced Neoplastic Transformation
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P2860
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@ast
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@en
type
label
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@ast
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@en
prefLabel
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@ast
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@en
P2860
P356
P1476
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
@en
P2093
J A DeCaprio
P2860
P304
P356
10.1128/MCB.15.10.5800
P407
P577
1995-10-01T00:00:00Z