The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells.
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Serine/Threonine kinases 3pK and MAPK-activated protein kinase 2 interact with the basic helix-loop-helix transcription factor E47 and repress its transcriptional activityCharacterization of ABF-1, a novel basic helix-loop-helix transcription factor expressed in activated B lymphocytes.Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathwaysThe class II trans-activator CIITA interacts with the TBP-associated factor TAFII32The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLFHelix-loop-helix proteins: regulators of transcription in eucaryotic organismsCritical role for a single leucine residue in leukemia induction by E2A-PBX1HEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticityA TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcriptionMitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3pCharacterization of the mUBC9-binding sites required for E2A protein degradationMechanism of transcriptional activation by the proto-oncogene Twist1Identification of the E2A gene products as regulatory targets of the G1 cyclin-dependent kinases.Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy.p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene.The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein bindingRole for homodimerization in growth deregulation by E2a fusion proteins.Functional diversity of human basic helix-loop-helix transcription factor TCF4 isoforms generated by alternative 5' exon usage and splicing.Regulation of immunoglobulin gene transcription in a teleost fish: identification, expression and functional properties of E2A in the channel catfish.The role of E2A-PBX1 in leukemogenesis.Shared structural features of the 9aaTAD family in complex with CBP.The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domainGene expression patterns define novel roles for E47 in cell cycle progression, cytokine-mediated signaling, and T lineage developmentEctopic expression of E47 or E12 promotes the death of E2A-deficient lymphomasA Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.Expansion of CTG18.1 Trinucleotide Repeat in TCF4 Is a Potent Driver of Fuchs' Corneal Dystrophy.Helix-loop-helix proteins and lymphocyte development.Induction of early B cell factor (EBF) and multiple B lineage genes by the basic helix-loop-helix transcription factor E12.Functional characterization of the transactivation properties of the PDX-1 homeodomain protein.Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activitiesDifferential involvement of E2A-corepressor interactions in distinct leukemogenic pathways.Enhancer-specific modulation of E protein activity.Basic helix loop helix (bHLH) transcription factor 3 (TCF3, E2A) is regulated by androgens in prostate cancer cells.Essential roles of Da transactivation domains in neurogenesis and in E(spl)-mediated repression.Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice.The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter.Overlapping expression of early B-cell factor and basic helix-loop-helix proteins as a mechanism to dictate B-lineage-specific activity of the lambda5 promoter.E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas.Analysis of the inhibition of MyoD activity by ITF-2B and full-length E12/E47.Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300.
P2860
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P2860
The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@ast
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@en
type
label
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@ast
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@en
prefLabel
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@ast
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@en
P2093
P2860
P356
P1476
The AD1 transactivation domain ...... erevisiae and mammalian cells.
@en
P2093
P2860
P304
P356
10.1128/MCB.16.1.121
P407
P577
1996-01-01T00:00:00Z