Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons
about
The role of secretory leukocyte proteinase inhibitor and elafin (elastase-specific inhibitor/skin-derived antileukoprotease) as alarm antiproteinases in inflammatory lung diseaseProgress towards gene therapy for cystic fibrosisThe role of chromatin in adenoviral vector functionLiver-targeted gene therapy: Approaches and challengesGutless adenovirus: last-generation adenovirus for gene therapyComparison of osteogenic potentials of human rat BMP4 and BMP6 gene therapy using [E1-] and [E1-,E2b-] adenoviral vectors.Ultrasound-assisted nonviral gene transfer of AQP1 to the irradiated minipig parotid gland restores fluid secretion.Production of adenovirus vectors and their use as a delivery system for influenza vaccines.Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin.Human gene therapy and imaging in neurological diseases.Single-chain antibody and its derivatives directed against vascular endothelial growth factor: application for antiangiogenic gene therapy.Comparison of replication-competent, first generation, and helper-dependent adenoviral vaccinesMechanism of protection against alcoholism by an alcohol dehydrogenase polymorphism: development of an animal model.Adenoviral vector immunity: its implications and circumvention strategies.Vector and helper genome rearrangements occur during production of helper-dependent adenoviral vectors.The influence of innate and pre-existing immunity on adenovirus therapyAdenoviral Vectors for Hemophilia Gene TherapyLarge-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories.Efficient, long-term hepatic gene transfer using clinically relevant HDAd doses by balloon occlusion catheter delivery in nonhuman primatesStrategies to modulate immune responses: a new frontier for gene therapyHepatic gene transfer as a means of tolerance induction to transgene productsIntensive pharmacological immunosuppression allows for repetitive liver gene transfer with recombinant adenovirus in nonhuman primatesGene and cell-mediated therapies for muscular dystrophy.Evaluation of cross-reactive cell-mediated immune responses among human, bovine and porcine adenoviruses.A novel bicistronic high-capacity gutless adenovirus vector that drives constitutive expression of herpes simplex virus type 1 thymidine kinase and tet-inducible expression of Flt3L for glioma therapeuticsGene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.Altering the Ad5 packaging domain affects the maturation of the Ad particles.Advancements in gene transfer-based therapy for hemophilia A.Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vectorA novel system for the production of fully deleted adenovirus vectors that does not require helper adenovirus.Improvements in adenoviral vector technology: overcoming barriers for gene therapy.Study of the efficacy, biodistribution, and safety profile of therapeutic gutless adenovirus vectors as a prelude to a phase I clinical trial for glioblastoma.Evaluation of adenovirus-delivered human CD59 as a potential therapy for AMD in a model of human membrane attack complex formation on murine RPE.The future potential for cocaine vaccines.Regulatable gutless adenovirus vectors sustain inducible transgene expression in the brain in the presence of an immune response against adenoviruses.Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.Viral and nonviral delivery systems for gene deliveryCurrent progress in the development of a prophylactic vaccine for HIV-1.Current strategies and future directions for eluding adenoviral vector immunityEncapsulation of recombinant adenovirus into alginate microspheres circumvents vector-specific immune response.
P2860
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P2860
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Administration of helper-depen ...... ected gene transfer in baboons
@ast
Administration of helper-depen ...... ected gene transfer in baboons
@en
type
label
Administration of helper-depen ...... ected gene transfer in baboons
@ast
Administration of helper-depen ...... ected gene transfer in baboons
@en
prefLabel
Administration of helper-depen ...... ected gene transfer in baboons
@ast
Administration of helper-depen ...... ected gene transfer in baboons
@en
P2093
P2860
P356
P1476
Administration of helper-depen ...... ected gene transfer in baboons
@en
P2093
A L Beaudet
E Aguilar-Córdova
F L Graham
P A Piedra
P2860
P304
12816-12821
P356
10.1073/PNAS.96.22.12816
P407
P50
P577
1999-10-01T00:00:00Z