The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.
about
Cloning and characterization of PHIP, a novel insulin receptor substrate-1 pleckstrin homology domain interacting proteinIRS-4 mediates protein kinase B signaling during insulin stimulation without promoting antiapoptosisHeregulin-dependent activation of phosphoinositide 3-kinase and Akt via the ErbB2/ErbB3 co-receptorThe COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signalingIndependent signaling by Drosophila insulin receptor for axon guidance and growth.Genetic control of size in Drosophila.Diabetic flies? Using Drosophila melanogaster to understand the causes of monogenic and genetically complex diseases.Integrating body and organ size in Drosophila: recent advances and outstanding problemsThe song of the old mother: reproductive senescence in female drosophila.Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in DrosophilaYMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal.Size assessment and growth control: how adult size is determined in insects.The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.Eat to reproduce: a key role for the insulin signaling pathway in adult insects.Molecular mechanisms of metabolic regulation by insulin in Drosophila.Depletion of insulin receptor substrate 2 reverses oncogenic transformation induced by v-src.Cellular compartmentalization in insulin action: altered signaling by a lipid-modified IRS-1.The pleckstrin homology and phosphotyrosine binding domains of insulin receptor substrate 1 mediate inhibition of apoptosis by insulinTransformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling.Insulin receptor substrate-1, p70S6K, and cell size in transformation and differentiation of hemopoietic cells.Characterization of Drosophila insulin receptor substrate.The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival.Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation.The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.The IRS-signalling system during insulin and cytokine action.Insulin reduces apoptosis and increases DNA synthesis and cell size via distinct signalling pathways in Drosophila Kc cells.Positive selection has driven the evolution of the Drosophila insulin-like receptor (InR) at different timescales.Cooperative transformation of 32D cells by the combined expression of IRS-1 and V-Ha-Ras.
P2860
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P2860
The Drosophila insulin receptor activates multiple signaling pathways but requires insulin receptor substrate proteins for DNA synthesis.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@ast
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@en
type
label
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@ast
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@en
prefLabel
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@ast
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@en
P2093
P2860
P356
P1476
The Drosophila insulin recepto ...... te proteins for DNA synthesis.
@en
P2093
J H Pierce
J Schlessinger
R Fernandez
T C Grammer
P2860
P304
P356
10.1128/MCB.16.5.2509
P407
P577
1996-05-01T00:00:00Z