Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes.
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Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytesAssociation of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulinProtein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytesOxidative stress impairs insulin but not platelet-derived growth factor signalling in 3T3-L1 adipocytesExpression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase BLiver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesisInsulin increases the association of Akt-2 with Glut4-containing vesiclesIdentification of the APS protein as a novel insulin receptor substratePRR14 is a novel activator of the PI3K pathway promoting lung carcinogenesis.Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle.Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes.Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathwaysNormal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetesRole of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.Selective PPARĪ³ modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice.Differential regulation of phosphoinositide 3-kinase adapter subunit variants by insulin in human skeletal muscle.SRF-dependent gene expression is required for PI3-kinase-regulated cell proliferation.Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerizationInsulin-stimulated glucose uptake occurs in specialized cells within the cumulus oocyte complex.Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis.Insulin receptor-independent upregulation of cellular glucose uptakeInsulin-mimetic signalling of synthetic phosphoinositolglycans in isolated rat adipocytes.Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress.Adipose tissue plasticity during catch-up fat driven by thrifty metabolism: relevance for muscle-adipose glucose redistribution during catch-up growth.Skeletal muscle insulin resistance: the interplay of local lipid excess and mitochondrial dysfunction.Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming.Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1).Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit.Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation.Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts.Sodium/myo-inositol cotransporter 1 and myo-inositol are essential for osteogenesis and bone formation.Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.Insulin signaling.Acute activation of Erk1/Erk2 and protein kinase B/akt proceed by independent pathways in multiple cell types.The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes.Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism.The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.
P2860
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P2860
Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes.
description
1997 nĆ® lÅ«n-bĆ»n
@nan
1997幓ć®č«ę
@ja
1997幓č«ę
@yue
1997幓č«ę
@zh-hant
1997幓č«ę
@zh-hk
1997幓č«ę
@zh-mo
1997幓č«ę
@zh-tw
1997幓č®ŗę
@wuu
1997幓č®ŗę
@zh
1997幓č®ŗę
@zh-cn
name
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@ast
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@en
type
label
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@ast
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@en
prefLabel
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@ast
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@en
P2860
P356
P1476
Differential effects of consti ...... ynthesis in 3T3-L1 adipocytes.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.1.190
P407
P577
1997-01-01T00:00:00Z