Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis.
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NRBF2 regulates macroautophagy as a component of Vps34 Complex IPIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesisHuman VPS34 and p150 are Rab7 interacting partnersPI(5)P regulates autophagosome biogenesishVps15, but not Ca2+/CaM, is required for the activity and regulation of hVps34 in mammalian cellsHuman VPS34 is required for internal vesicle formation within multivesicular endosomesInterchangeable but essential functions of SNX1 and SNX2 in the association of retromer with endosomes and the trafficking of mannose 6-phosphate receptorsPhosphoinositide 3-kinase signalling in breast cancer: how big a role might it play?Deciphering the roles of phosphoinositide lipids in phagolysosome biogenesisEffect of TRB3 on insulin and nutrient-stimulated hepatic p70 S6 kinase activityOverexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturationRegulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3-kinase activityMechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis.Dynamic traffic through the recycling compartment couples the metal transporter Nramp2 (DMT1) with the transferrin receptorComplementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinasesRabs and their effectors: achieving specificity in membrane trafficThe SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase.Essential role of Ca2+/calmodulin in Early Endosome Antigen-1 localization.A Trypanosoma cruzi phosphatidylinositol 3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis.Phosphatidylinositol-3-OH kinases are Rab5 effectors.The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphomaBECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein.AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyveHuman immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinaseThe first step of adenovirus type 2 disassembly occurs at the cell surface, independently of endocytosis and escape to the cytosol.Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane traffickingRegulators of membrane trafficking and Mycobacterium tuberculosis phagosome maturation block.Phosphatidylinositol 3-kinase and the control of endosome dynamics: new players defined by structural motifs.Organelle membrane proteomics reveals differential influence of mycobacterial lipoglycans on macrophage phagosome maturation and autophagosome accumulation.VAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts.Important relationships between Rab and MICAL proteins in endocytic trafficking.Multiple host kinases contribute to Akt activation during Salmonella infection.Intracellular segregation of phosphatidylinositol-3,4,5-trisphosphate by insulin-dependent actin remodeling in L6 skeletal muscle cellsTranscytosis: crossing cellular barriers.Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis.Class III PI 3-kinase is the main source of PtdIns3P substrate and membrane recruitment signal for PIKfyve constitutive function in podocyte endomembrane homeostasisThe Arf GTPase-activating protein ASAP1 regulates the actin cytoskeletonInhibitors of phosphoinositide 3-kinase cause defects in the postendocytic sorting of beta2-adrenergic receptors.Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins.Evidence for apical endocytosis in polarized hepatic cells: phosphoinositide 3-kinase inhibitors lead to the lysosomal accumulation of resident apical plasma membrane proteins
P2860
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P2860
Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@ast
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@en
type
label
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@ast
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@en
prefLabel
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@ast
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@en
P2093
P2860
P356
P1476
Distinct roles for the p110alp ...... cytoskeleton, and mitogenesis.
@en
P2093
P2860
P304
P356
10.1083/JCB.143.6.1647
P407
P577
1998-12-01T00:00:00Z