Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.
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A dedicated promoter drives constitutive expression of the cell-autonomous immune resistance GTPase, Irga6 (IIGP1) in mouse liverValue of monitoring Nrf2 activity for the detection of chemical and oxidative stressModels and methods for in vitro testing of hepatic gap junctional communicationPrimary hepatocytes and their cultures in liver apoptosis researchUsage of adenovirus expressing thymidine kinase mediated hepatocellular damage for enabling mouse liver repopulation with allogenic or xenogenic hepatocytesMaturation of induced pluripotent stem cell derived hepatocytes by 3D-cultureCholesterol-secreting and statin-responsive hepatocytes from human ES and iPS cells to model hepatic involvement in cardiovascular healthCross-species gene expression analysis of species specific differences in the preclinical assessment of pharmaceutical compoundsMicroRNA profiling during cardiomyocyte-specific differentiation of murine embryonic stem cells based on two different miRNA array platformsStem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryAnnulus fibrosus cell characteristics are a potential source of intervertebral disc pathogenesis.Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.Liver-enriched transcription factors are critical for the expression of hepatocyte marker genes in mES-derived hepatocyte-lineage cells.The nitric oxide donor S-nitrosoglutathione reduces apoptotic primary liver cell loss in a three-dimensional perfusion bioreactor culture model developed for liver supportCharacterization of spontaneous cell death in monolayer cultures of primary hepatocytes.Organomatics and organometrics: Novel platforms for long-term whole-organ culture.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acidSandwich-cultured hepatocytes: utility for in vitro exploration of hepatobiliary drug disposition and drug-induced hepatotoxicity.From whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitationsRole of connexin-related signalling in hepatic homeostasis and its relevance for liver-based in vitro modellingHistone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology.In vitro-in vivo translation of lipid nanoparticles for hepatocellular siRNA delivery.Supportive development of functional tissues for biomedical research using the MINUSHEET® perfusion system.Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.Stem cells for liver tissue repair: current knowledge and perspectivesRecent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Cell sources for in vitro human liver cell culture models.Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis.In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art.Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity.Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes.Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.Transcriptional, Functional, and Mechanistic Comparisons of Stem Cell-Derived Hepatocytes, HepaRG Cells, and Three-Dimensional Human Hepatocyte Spheroids as Predictive In Vitro Systems for Drug-Induced Liver Injury.Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening.Modifications in connexin expression in liver development and cancer.Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies.Hepatitis C, innate immunity and alcohol: friends or foes?Experimental models of hepatitis B and C - new insights and progress
P2860
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P2860
Molecular mechanisms underlying the dedifferentiation process of isolated hepatocytes and their cultures.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Molecular mechanisms underlyin ...... epatocytes and their cultures.
@ast
Molecular mechanisms underlyin ...... epatocytes and their cultures.
@en
type
label
Molecular mechanisms underlyin ...... epatocytes and their cultures.
@ast
Molecular mechanisms underlyin ...... epatocytes and their cultures.
@en
prefLabel
Molecular mechanisms underlyin ...... epatocytes and their cultures.
@ast
Molecular mechanisms underlyin ...... epatocytes and their cultures.
@en
P2093
P1476
Molecular mechanisms underlyin ...... hepatocytes and their cultures
@en
P2093
Greetje Elaut
Peggy Papeleu
Sarah Snykers
Tamara Vanhaecke
Tom Henkens
Vera Rogiers
P304
P356
10.2174/138920006778017759
P407
P577
2006-08-01T00:00:00Z