Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec
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A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomainsTxk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cellsCARMA1 is required for Akt-mediated NF-kappaB activation in T cells.Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fatesSHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2).Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression.Genome-wide interaction-based association analysis identified multiple new susceptibility Loci for common diseasesStress signaling by Tec tyrosine kinase in the ischemic myocardium.Lipid signaling in T-cell development and functionEarly phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways.G6f-like is an ITAM-containing collagen receptor in thrombocytes.Itk: the rheostat of the T cell response.Ibrutinib treatment ameliorates murine chronic graft-versus-host disease.Reciprocal regulation of C-Maf tyrosine phosphorylation by Tec and Ptpn22.A molecular and functional analysis of large granular lymphocyte expansions in patients with chronic myelogenous leukemia treated with tyrosine kinase inhibitorsTEC-family kinases: regulators of T-helper-cell differentiation.A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis.Tec kinases, actin, and cell adhesion.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkTEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma.ITK inhibitors in inflammation and immune-mediated disorders.PKC-θ is a drug target for prevention of T cell-mediated autoimmunity and allograft rejection.The role of Tec family kinases in the regulation of T-helper-cell differentiation.The function of sub-synaptic vesicles during T-cell activation.Do signalling endosomes play a role in T cell activation?Regulation of ras exchange factors and cellular localization of ras activation by lipid messengers in T cells.Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling.Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling.Anti-tumor efficacy study of the Bruton's tyrosine kinase (BTK) inhibitor, ONO/GS-4059, in combination with the glycoengineered type II anti-CD20 monoclonal antibody obinutuzumab (GA101) demonstrates superior in vivo efficacy compared to ONO/GS-4059NF-kappaB regulates the transcription of protein tyrosine kinase Tec.Collagen promotes sustained glycoprotein VI signaling in platelets and cell lines.The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade.A kinase independent function for Tec kinase ITK in regulating antigen receptor induced serum response factor activation.Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal- and luminal-like breast cancer xenografts.CLEC-2 activates Syk through dimerization.Intervention of PKC-θ as an immunosuppressive regimen.Pharmacological targeting of phosphoinositide lipid kinases and phosphatases in the immune system: success, disappointment, and new opportunities.
P2860
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P2860
Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Expression and function of Tec ...... ence for a unique role for Tec
@ast
Expression and function of Tec ...... ence for a unique role for Tec
@en
type
label
Expression and function of Tec ...... ence for a unique role for Tec
@ast
Expression and function of Tec ...... ence for a unique role for Tec
@en
prefLabel
Expression and function of Tec ...... ence for a unique role for Tec
@ast
Expression and function of Tec ...... ence for a unique role for Tec
@en
P2860
P50
P1476
Expression and function of Tec ...... ence for a unique role for Tec
@en
P2093
Jennifer Su
Marianne N Mollenauer
P2860
P304
P356
10.1128/MCB.24.6.2455-2466.2004
P407
P577
2004-03-01T00:00:00Z