PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.
about
Abnormal degradation of the neuronal stress-protective transcription factor HSF1 in Huntington's disease.Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells.Induced Pluripotent Stem Cells in Huntington's Disease Research: Progress and Opportunity.Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for In Vitro Modeling of Neurological Disorders Pathology and Therapy.PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation.Telmisartan Activates PPARδ to Improve Symptoms of Unpredictable Chronic Mild Stress-Induced Depression in Mice.Huntington disease: Boosting PPARδ blocks neurodegeneration.Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity.PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.Representing Diversity in the Dish: Using Patient-Derived in Vitro Models to Recreate the Heterogeneity of Neurological Disease.Transcriptional regulatory networks underlying gene expression changes in Huntington's disease.Therapy development in Huntington disease: From current strategies to emerging opportunities.Peroxisome Proliferator Activated Receptor Agonists Modulate Transposable Element Expression in Brain and Liver
P2860
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P2860
PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@ast
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@en
type
label
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@ast
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@en
prefLabel
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@ast
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@en
P2093
P2860
P50
P356
P1433
P1476
PPAR-δ is repressed in Hunting ...... n be targeted therapeutically.
@en
P2093
Albert R La Spada
Anne Buttgereit
April L Flores
Bryce L Sopher
Eduardo R Lazarowski
Gavin K Magnuson
Gene W Yeo
Helen C Miranda
Kunal R Sampat
Mark-Joseph Manalang Torres
P2860
P2888
P356
10.1038/NM.4003
P407
P577
2015-12-07T00:00:00Z
P6179
1031712104