Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation.
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Conformational diversity in prion protein variants influences intermolecular beta-sheet formationPrionsCellular prion protein conformation and functionChronic wasting disease prions in elk antler velvetA systems approach to prion diseaseConversion of alpha-lactalbumin to a protein inducing apoptosisPrediction of "hot spots" of aggregation in disease-linked polypeptidesProgress on low susceptibility mechanisms of transmissible spongiform encephalopathiesEffective gene therapy in a mouse model of prion diseasesTrans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactorEvidence that bank vole PrP is a universal acceptor for prionsAn intercalation mechanism as a mode of action exerted by psychotropic drugs: results of altered phospholipid substrate availabilities in membranes?NMR solution structure of the human prion proteinNMR structure of the bovine prion proteinNMR structures of three single-residue variants of the human prion proteinSolution structure of the E200K variant of human prion protein. Implications for the mechanism of pathogenesis in familial prion diseasesTwo different neurodegenerative diseases caused by proteins with similar structuresSheep prion protein synthetic peptide spanning helix 1 and beta-strand 2 (residues 142-166) shows beta-hairpin structure in solutionPrion Fibrillization Is Mediated by a Native Structural Element That Comprises Helices H2 and H3Unique Structural Characteristics of the Rabbit Prion ProteinNMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural FeaturesSolution Structure and Dynamics of the I214V Mutant of the Rabbit Prion ProteinN-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion ProteinsStructural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphismSolution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoformChanging a single amino acid in the N-terminus of murine PrP alters TSE incubation time across three species barriers.Strain-specified relative conformational stability of the scrapie prion proteinIdentification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptorIntroducing a rigid loop structure from deer into mouse prion protein increases its propensity for misfolding in vitroCritical significance of the region between Helix 1 and 2 for efficient dominant-negative inhibition by conversion-incompetent prion proteinCRISPR-Cas9-based knockout of the prion protein and its effect on the proteomePrion fragment peptides are digested with membrane type matrix metalloproteinases and acquire enzyme resistance through Cu²⁺-bindingVariety of antiprion compounds discovered through an in silico screen based on cellular-form prion protein structure: Correlation between antiprion activity and binding affinity.Pulling rabbits to reveal the secrets of the prion proteinGlobular domain of the prion protein needs to be unlocked by domain swapping to support prion protein conversionSpecific biarsenical labeling of cell surface proteins allows fluorescent- and biotin-tagging of amyloid precursor protein and prion proteins.The dominant-negative effect of the Q218K variant of the prion protein does not require protein X.Copper binding to the prion protein: structural implications of four identical cooperative binding sitesMolecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.Human prion protein sequence elements impede cross-species chronic wasting disease transmission.
P2860
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P2860
Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Evidence for protein X binding ...... ing scrapie prion propagation.
@ast
Evidence for protein X binding ...... ing scrapie prion propagation.
@en
type
label
Evidence for protein X binding ...... ing scrapie prion propagation.
@ast
Evidence for protein X binding ...... ing scrapie prion propagation.
@en
prefLabel
Evidence for protein X binding ...... ing scrapie prion propagation.
@ast
Evidence for protein X binding ...... ing scrapie prion propagation.
@en
P2093
P2860
P356
P1476
Evidence for protein X binding ...... ing scrapie prion propagation.
@en
P2093
P2860
P304
10069-10074
P356
10.1073/PNAS.94.19.10069
P407
P577
1997-09-01T00:00:00Z