Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
about
Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosisEnhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamicsPlk phosphorylation regulates the microtubule-stabilizing protein TCTP.Paclitaxel-dependent cell lines reveal a novel drug activity.Microtubules do not promote mitotic slippage when the spindle assembly checkpoint cannot be satisfied.Checkpoint genes required to delay cell division in response to nocodazole respond to impaired kinetochore function in the yeast Saccharomyces cerevisiae.Taxol suppresses dynamics of individual microtubules in living human tumor cellsModulating sensitivity to drug-induced apoptosis: the future for chemotherapy?Hitting the brakes: targeting microtubule motors in cancerA novel microtubule inhibitor 4SC-207 with anti-proliferative activity in taxane-resistant cellsMitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells.How morphological constraints affect axonal polarity in mouse neuronsLaulimalide induces dose-dependent modulation of microtubule behaviour in the C. elegans embryoEffects of paclitaxel on EGFR endocytic trafficking revealed using quantum dot tracking in single cellsIntegrin-linked kinase regulates interphase and mitotic microtubule dynamicsPhototriggerable 2',7-caged paclitaxelPlk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell linesMicrotubule-binding agents: a dynamic field of cancer therapeutics.Fine tuning chemotherapy to match BRCA1 statusRecycling of the cell adhesion molecule L1 in axonal growth cones.NAP1 acts with Clb1 to perform mitotic functions and to suppress polar bud growth in budding yeast.Pharmacogenomics in Pediatric Oncology: Review of Gene-Drug Associations for Clinical UseCell cycle regulation of the endogenous wild type Bloom's syndrome DNA helicaseKinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerasesAntiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule endsModulation of endogenous beta-tubulin isotype expression as a result of human beta(III)cDNA transfection into prostate carcinoma cellsInactivation of wild-type p53 by a dominant negative mutant renders MCF-7 cells resistant to tubulin-binding agent cytotoxicityPhyllanthus emblica Fruit Extract Activates Spindle Assembly Checkpoint, Prevents Mitotic Aberrations and Genomic Instability in Human Colon Epithelial NCM460 Cells.Taxol crystals can masquerade as stabilized microtubulesIntegrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screenPraziquantel synergistically enhances paclitaxel efficacy to inhibit cancer cell growthHigh-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markersMutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathwayLocalization of Mad2 to kinetochores depends on microtubule attachment, not tensionClass V β-tubulin alters dynamic instability and stimulates microtubule detachment from centrosomes.Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint.The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work.Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends.Axon extension in the fast and slow lanes: substratum-dependent engagement of myosin II functions.
P2860
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P2860
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Mechanism of mitotic block and ...... by taxol at low concentrations
@ast
Mechanism of mitotic block and ...... by taxol at low concentrations
@en
type
label
Mechanism of mitotic block and ...... by taxol at low concentrations
@ast
Mechanism of mitotic block and ...... by taxol at low concentrations
@en
prefLabel
Mechanism of mitotic block and ...... by taxol at low concentrations
@ast
Mechanism of mitotic block and ...... by taxol at low concentrations
@en
P2093
P2860
P356
P1476
Mechanism of mitotic block and ...... by taxol at low concentrations
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.20.9552
P407
P577
1993-10-01T00:00:00Z