Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica. - Wikidata - awgldk - TriplyDB

Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica.

Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica.

http://www.wikidata.org/entity/Q36603928

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Mammalian nicotinic acetylcholine receptors: from structure to function Protein Folding Determinants: Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡Galanthamine and Non-competitive Inhibitor Binding to ACh-binding Protein: Evidence for a Binding Site on Non-α-subunit Interfaces of Heteromeric Neuronal Nicotinic Receptors AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor Main Immunogenic Region Structure Promotes Binding of Conformation-Dependent Myasthenia Gravis Autoantibodies, Nicotinic Acetylcholine Receptor Conformation Maturation, and Agonist Sensitivity Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism Acetylcholine-Binding Protein in the Hemolymph of the Planorbid Snail Biomphalaria glabrata Is a Pentagonal Dodecahedron (60 Subunits)Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4β2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations Escherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs)Marine Toxins Targeting Ion Channels Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.A virtual screening study of the acetylcholine binding protein using a relaxed-complex approach Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors.New insights into the GABA(A) receptor structure and orthosteric ligand binding: receptor modeling guided by experimental data.Homology modeling and molecular dynamics simulations of the glycine receptor ligand binding domain Efficient expression of acetylcholine-binding protein from Aplysia californica in Bac-to-Bac system Virtual screening against acetylcholine binding protein Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor.Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.Structural answers and persistent questions about how nicotinic receptors work.Dodecyl maltopyranoside enabled purification of active human GABA type A receptors for deep and direct proteomic sequencing Virtual screening against alpha-cobratoxin Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α1(2)βγδ nAChRs.Mapping the elusive neonicotinoid binding site.The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit.Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates.Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors.Identification and functional characterization of a novel acetylcholine-binding protein from the marine annelid Capitella teleta Development of a solid-phase receptor-based assay for the detection of cyclic imines using a microsphere-flow cytometry system.Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes.Single-channel current through nicotinic receptor produced by closure of binding site C-loop.Effect of homologous serotonin receptor loop substitutions on the heterologous expression in Pichia of a chimeric acetylcholine-binding protein with alpha-bungarotoxin-binding activity Structural basis for alpha-conotoxin potency and selectivity.On the origin of ion selectivity in the Cys-loop receptor family.

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P2860

Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica.

http://www.wikidata.org/entity/Q36603928

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2004 nî lūn-bûn

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Structural and ligand recognit ...... tein from Aplysia californica.

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Structural and ligand recognit ...... tein from Aplysia californica.

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Structural and ligand recognit ...... tein from Aplysia californica.

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Journal of Biological Chemistry

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Structural and ligand recognit ...... tein from Aplysia californica.

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P2093

Palmer Taylor

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Scott B Hansen

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Todd T Talley

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Zoran Radic

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P2860

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Structure and gating mechanism of the acetylcholine receptor pore

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

Use of a snake venom toxin to characterize the cholinergic receptor protein

Nicotinic receptors at the amino acid level.

Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes.

Coupling of agonist binding to channel gating in the GABA(A) receptor.

Emerging structure of the nicotinic acetylcholine receptors.

The nicotinic receptor ligand binding domain.

Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.

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24197-24202

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10.1074/JBC.M402452200

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23

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4762456

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