A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
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PqsD is responsible for the synthesis of 2,4-dihydroxyquinoline, an extracellular metabolite produced by Pseudomonas aeruginosaCharacterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreusBiochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide BiosynthesisOxidative dearomatisation: the key step of sorbicillinoid biosynthesis†Electronic supplementary information (ESI) available: Containing all experimental details. See DOI: 10.1039/c3sc52911hClick here for additional data file.Insights into the biosynthesis of 12-membered resorcylic acid lactones from heterologous production in Saccharomyces cerevisiae.Cyclization of aromatic polyketides from bacteria and fungiIsolation and characterization of a reducing polyketide synthase gene from the lichen-forming fungus Usnea longissima.Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains.Insights into radicicol biosynthesis via heterologous synthesis of intermediates and analogsDiversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases.Recent advancements in the biosynthetic mechanisms for polyketide-derived mycotoxins.Demonstration of starter unit interprotein transfer from a fatty acid synthase to a multidomain, nonreducing polyketide synthase.New insights into the formation of fungal aromatic polyketides.Starter unit flexibility for engineered product synthesis by the nonreducing polyketide synthase PksARecent progress regarding the bioactivities, biosynthesis and synthesis of naturally occurring resorcinolic macrolides.Rational reprogramming of fungal polyketide first-ring cyclizationEngineered biosynthesis of bacterial aromatic polyketides in Escherichia coli.Thioesterase domains of fungal nonreducing polyketide synthases act as decision gates during combinatorial biosynthesis.Three new resorcylic acid derivatives from Sporotrichum laxumIn vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents.Structural analysis of protein-protein interactions in type I polyketide synthasesHeterologous expression systems for polyketide synthases.Diversity-Oriented Combinatorial Biosynthesis of Hybrid Polyketide Scaffolds from Azaphilone and Benzenediol Lactone Biosynthons.PKS and NRPS release mechanisms.A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases.Convergent strategies in biosynthesis.Explorations of fungal biosynthesis of reduced polyketides - a personal viewpoint.Saccharomyces cerevisiae as a tool for mining, studying and engineering fungal polyketide synthases.Total biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase α: heterologous expression of four biosynthetic genes in Aspergillus oryzae.Identification of a type III polyketide synthase involved in the biosynthesis of spirolaxine.Characterization of a novel type of oxidative decarboxylase involved in the biosynthesis of the styryl moiety of chondrochloren from an acylated tyrosine.Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis.Hidden function of catalytic domain in 6-methylsalicylic acid synthase for product release.γ-Resorcylate catabolic-pathway genes in the soil actinomycete Rhodococcus jostii RHA1.Complete reconstitution of a highly reducing iterative polyketide synthase.Production of New Cladosporin Analogues by Reconstitution of the Polyketide Synthases Responsible for the Biosynthesis of this Antimalarial Agent.Chemical chain termination resolves the timing of ketoreduction in a partially reducing iterative type I polyketide synthase.Navigating the fungal polyketide chemical space: from genes to molecules.A thioesterase from an iterative fungal polyketide synthase shows macrocyclization and cross coupling activity and may play a role in controlling iterative cycling through product offloading.LAP5 and LAP6 encode anther-specific proteins with similarity to chalcone synthase essential for pollen exine development in Arabidopsis.
P2860
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P2860
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@ast
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@en
type
label
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@ast
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@en
prefLabel
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@ast
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@en
P2093
P2860
P356
P1476
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
@en
P2093
P2860
P304
P356
10.1073/PNAS.0800657105
P407
P577
2008-04-21T00:00:00Z