Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.
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The effect of ABCB1 polymorphisms on the outcome of breast cancer treatmentRacial Differences in the Cholesterol-Lowering Effect of Statin.Pharmacokinetic interactions between glimepiride and rosuvastatin in healthy Korean subjects: does the SLCO1B1 or CYP2C9 genetic polymorphism affect these drug interactions? Observations and introspection of the bioanalysis.Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment.Interindividual differences in phytochemical metabolism and dispositionPolymorphism in human organic cation transporters and metformin action.Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents.Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.Organic cation transporters and their roles in antiretroviral drug disposition.Gender and interindividual variability in pharmacokinetics.The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.Genetic polymorphism in metabolism and host defense enzymes: implications for human health risk assessment.Developmental pharmacogenomics.The primary role of hepatic metabolism in idiosyncratic drug-induced liver injury.Pharmacogenetics of drug-induced birth defects: the role of polymorphisms of placental transporter proteins.Effect of Liver Disease on Hepatic Transporter Expression and Function.Organic Cation Transporter 2 (OCT2/SLC22A2) Gene Variation in the South African Bantu-Speaking Population and Functional Promoter Variants.Effects of genetic variation in the novel organic cation transporter, OCTN1, on the renal clearance of gabapentin.Evaluation of pharmacokinetic parameters and dipeptidyl peptidase-4 inhibition following single doses of sitagliptin in healthy, young Japanese malesABCB1 3435TT and ABCG2 421CC genotypes were significantly associated with longer progression-free survival in Chinese breast cancer patients.Association of ABCG2 polymorphism with clinical efficacy of imatinib in patients with gastrointestinal stromal tumor.
P2860
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P2860
Genetic polymorphisms of drug transporters: pharmacokinetic and pharmacodynamic consequences in pharmacotherapy.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Genetic polymorphisms of drug ...... nsequences in pharmacotherapy.
@en
type
label
Genetic polymorphisms of drug ...... nsequences in pharmacotherapy.
@en
prefLabel
Genetic polymorphisms of drug ...... nsequences in pharmacotherapy.
@en
P2093
P2860
P356
P1476
Genetic polymorphisms of drug ...... nsequences in pharmacotherapy.
@en
P2093
Hiroshi Takane
Ichiro Ieiri
Kenji Otsubo
Shun Higuchi
Takeshi Hirota
P2860
P304
P356
10.1517/17425255.2.5.651
P407
P577
2006-10-01T00:00:00Z