PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.
about
In situ quantification of HER2-protein tyrosine kinase 6 (PTK6) protein-protein complexes in paraffin sections from breast cancer tissuesSignal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factorBrk is coamplified with ErbB2 to promote proliferation in breast cancerPI3K-independent AKT activation in cancers: a treasure trove for novel therapeuticsLow expression of PTK6/Brk predicts poor prognosis in patients with laryngeal squamous cell carcinoma.Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma.The marine-derived sipholenol A-4-O-3',4'-dichlorobenzoate inhibits breast cancer growth and motility in vitro and in vivo through the suppression of Brk and FAK signaling.PTK6 regulates IGF-1-induced anchorage-independent survival.Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRKEvolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapyHIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion.PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors.The epidermal growth factor receptor family in breast cancer.A comprehensive characterization of genome-wide copy number aberrations in colorectal cancer reveals novel oncogenes and patterns of alterationsCytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells.BRK targets Dok1 for ubiquitin-mediated proteasomal degradation to promote cell proliferation and migration.PTK6 promotes cancer migration and invasion in pancreatic cancer cells dependent on ERK signaling.uPAR enhances malignant potential of triple-negative breast cancer by directly interacting with uPA and IGF1R.Constitutive activation of breast tumor kinase accelerates cell migration and tumor growth in vivo.Identification of BRCA1-like triple-negative breast cancers by quantitative multiplex-ligation-dependent probe amplification (MLPA) analysis of BRCA1-associated chromosomal regions: a validation study.Overexpression of Kinesin Associated Protein 3 (KIFAP3) in Breast CancerRadiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cellsThe impact of cysteine-rich intestinal protein 1 (CRIP1) in human breast cancerPrognostic value of protein tyrosine kinase 6 (PTK6) for long-term survival of breast cancer patients.Protein tyrosine kinase 6 is associated with nasopharyngeal carcinoma poor prognosis and metastasis.HER2 regulates Brk/PTK6 stability via upregulating calpastatin, an inhibitor of calpain.Somatic copy number changes in DPYD are associated with lower risk of recurrence in triple-negative breast cancers.Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage.MiR-221/-222 differentiate prognostic groups in advanced breast cancers and influence cell invasion.Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer.Protein tyrosine kinase 6 regulates mammary gland tumorigenesis in mouse models.Human epidermal growth factor receptor 4 (HER4) is a favorable prognostic marker of breast cancer: a systematic review and meta-analysis.Human Epidermal Growth Factor Receptor-3 mRNA Expression as a Prognostic Marker for Invasive Duct Carcinoma not Otherwise Specified.Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer.Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling.EGFR overexpression relates to triple negative profile and poor prognosis in breast cancer patients in Tunisia.Optimization of marine triterpene sipholenols as inhibitors of breast cancer migration and invasion.Impact of protein tyrosine kinase 6 (PTK6) on human epidermal growth factor receptor (HER) signalling in breast cancer.Downregulated expression of PTK6 is correlated with poor survival in esophageal squamous cell carcinoma.
P2860
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P2860
PTK (protein tyrosine kinase)-6 and HER2 and 4, but not HER1 and 3 predict long-term survival in breast carcinomas.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas.
@ast
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas.
@en
type
label
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas.
@ast
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas.
@en
prefLabel
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas.
@ast
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas.
@en
P2093
P2860
P356
P1476
PTK (protein tyrosine kinase)- ...... survival in breast carcinomas
@en
P2093
H Braselmann
J M S Bartlett
T Fornander
P2860
P2888
P304
P356
10.1038/SJ.BJC.6603613
P407
P577
2007-02-13T00:00:00Z