Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle. - Wikidata - awgldk - TriplyDB

Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle.

Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle.

http://www.wikidata.org/entity/Q36615175

about

STIM and ORAI proteins in the nervous system High glucose and diabetes enhanced store-operated Ca(2+) entry and increased expression of its signaling proteins in mesangial cells.Potent functional uncoupling between STIM1 and Orai1 by dimeric 2-aminodiphenyl borinate analogs.Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia.Genomic structure and marker-derived gene networks for growth and meat quality traits of Brazilian Nelore beef cattle Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle.Differential roles of the C and N termini of Orai1 protein in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation STIM1-dependent Ca(2+) microdomains are required for myofilament remodeling and signaling in the heart.Emerging roles of Orai3 in pathophysiology.Symphony of vascular contraction: how smooth muscle cells lose harmony to signal increased vascular resistance in hypertension.Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function.What role for store-operated Ca²⁺ entry in muscle?Changing calcium: CRAC channel (STIM and Orai) expression, splicing, and posttranslational modifiers.Role of STIM2 in cell function and physiopathology.Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry.Stim1 Regulates Enamel Mineralization and Ameloblast Modulation.Differential role for stromal interacting molecule 1 in the regulation of vascular function.The Actin-Binding Protein Drebrin Inhibits Neointimal Hyperplasia.Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.The STIM1-binding site nexus remotely controls Orai1 channel gating.Cardiovascular and Hemostatic Disorders: Role of STIM and Orai Proteins in Vascular Disorders.Accumulation of STIM1 is associated with the degenerative muscle fibre phenotype in ALS and other neurogenic atrophies.The Complex Role of Store Operated Calcium Entry Pathways and Related Proteins in the Function of Cardiac, Skeletal and Vascular Smooth Muscle Cells.STIM1 Knockout Enhances PDGF-Mediated Ca2+ Signaling through Upregulation of the PDGFR⁻PLCγ⁻STIM2 Cascade.

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Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle.

http://www.wikidata.org/entity/Q36615175

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Targeted STIM deletion impairs ...... , and growth of smooth muscle.

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Targeted STIM deletion impairs ...... , and growth of smooth muscle.

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type

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Targeted STIM deletion impairs ...... , and growth of smooth muscle.

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Targeted STIM deletion impairs ...... , and growth of smooth muscle.

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Targeted STIM deletion impairs ...... , and growth of smooth muscle.

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Targeted STIM deletion impairs ...... , and growth of smooth muscle.

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Donald L Gill

http://www.w3.org/2001/XMLSchema#string

Hong Wang

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Hui Gao

http://www.w3.org/2001/XMLSchema#string

Michael Autieri

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Muniswamy Madesh

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Rajesh Kumar Gandhirajan

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Rosario Scalia

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Salvatore Mancarella

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Santhi Potireddy

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Steven R Houser

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P2860

STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry

STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels

STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx

STIM proteins: dynamic calcium signal transducers

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

STIM1, an essential and conserved component of store-operated Ca2+ channel function

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

Molecular regulation of vascular smooth muscle cell differentiation in development and disease

A global double-fluorescent Cre reporter mouse

Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation.

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893-906

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10.1096/FJ.12-215293

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3

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27

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23159931

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3574286

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