Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
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Mutational heterogeneity in cancer and the search for new cancer-associated genesModulating splicing with small molecular inhibitors of the spliceosomeThe clinical implications of gene mutations in chronic lymphocytic leukaemiaCancer Evolution and the Limits of Predictability in Precision Cancer MedicineDifferent Facets of Copy Number Changes: Permanent, Transient, and AdaptiveIs lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells?The influence of subclonal resistance mutations on targeted cancer therapyRegulation of deoxynucleotide metabolism in cancer: novel mechanisms and therapeutic implicationsCurrent and future molecular profiling of cancer by next-generation sequencingTumor-Derived Cell Lines as Molecular Models of Cancer PharmacogenomicsTargeting ATM-deficient CLL through interference with DNA repair pathwaysTranslational implications of tumor heterogeneityDeciphering the molecular landscape in chronic lymphocytic leukemia: time frame of disease evolutionDeciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicineCancer heterogeneity--a multifaceted viewEndogenous retroviruses and the development of cancerTumour heterogeneity and the evolution of polyclonal drug resistanceIntratumoral heterogeneity: Clonal cooperation in epithelial-to-mesenchymal transition and metastasisCancer evolution: mathematical models and computational inferenceNanomedicine therapeutic approaches to overcome cancer drug resistanceHeterogeneity in immune responses: from populations to single cellsThe pathogenesis of chronic lymphocytic leukemiaClonal evolution in hematological malignancies and therapeutic implicationsCharacterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to diseaseSciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolutionThe mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTPSF3B1 mutations in chronic lymphocytic leukemia.Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinibRecurrent mutations refine prognosis in chronic lymphocytic leukemia.Loss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck CancerClinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.Secondary mutations as mediators of resistance to targeted therapy in leukemiaGenomic and epigenomic heterogeneity in chronic lymphocytic leukemiaExome sequencing identifies BRAF mutations in papillary craniopharyngiomasSomatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesisAge-related mutations associated with clonal hematopoietic expansion and malignanciesEvolution of multiple cell clones over a 29-year period of a CLL patientBCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal CancerEndothelin-1 promotes survival and chemoresistance in chronic lymphocytic leukemia B cells through ETA receptorConceptualizing cancer drugs as classifiers
P2860
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P2860
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@ast
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@en
type
label
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@ast
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@en
prefLabel
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@ast
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@en
P2093
P2860
P50
P1433
P1476
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
@en
P2093
Aaron McKenna
Andrey Sivachenko
Bethany Tesar
Catherine J Wu
Chip Stewart
Dan A Landau
Donna Neuberg
Jennifer R Brown
Kristen Stevenson
P2860
P304
P356
10.1016/J.CELL.2013.01.019
P407
P50
P577
2013-02-01T00:00:00Z