Identification and characterization of the ICP22 protein of equine herpesvirus 1.
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The EICP22 protein of equine herpesvirus 1 physically interacts with the immediate-early protein and with itself to form dimers and higher-order complexesCharacterization of the trans-activation properties of equine herpesvirus 1 EICP0 proteinMapping the sequences that mediate interaction of the equine herpesvirus 1 immediate-early protein and human TFIIB.The equine herpesvirus-1 (EHV-1) IR3 transcript downregulates expression of the IE gene and the absence of IR3 gene expression alters EHV-1 biological properties and virulence.Properties of an equine herpesvirus 1 mutant devoid of the internal inverted repeat sequence of the genomic short region.ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.The early UL3 gene of equine herpesvirus-1 encodes a tegument protein not essential for replication or virulence in the mouseRegulatory function of the equine herpesvirus 1 ICP27 gene product.The transcriptional regulatory proteins encoded by varicella-zoster virus open reading frames (ORFs) 4 and 63, but not ORF 61, are associated with purified virus particles.Phosphorylation and nuclear localization of the varicella-zoster virus gene 63 protein.The ICP22 protein of equine herpesvirus 1 cooperates with the IE protein to regulate viral gene expression.The equine herpesvirus-1 IR3 gene that lies antisense to the sole immediate-early (IE) gene is trans-activated by the IE protein, and is poorly expressed to a protein.Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication.Full trans-activation mediated by the immediate-early protein of equine herpesvirus 1 requires a consensus TATA box, but not its cognate binding sequence.Deletion of the UL4 gene sequence of equine herpesvirus 1 precludes the generation of defective interfering particlesBiological and genotypic properties of defective interfering particles of equine herpesvirus 1 that mediate persistent infection.The IR4 auxiliary regulatory protein expands the in vitro host range of equine herpesvirus 1 and is essential for pathogenesis in the murine model.Immunization with Attenuated Equine Herpesvirus 1 Strain KyA Induces Innate Immune Responses That Protect Mice from Lethal Challenge.Expression of an equine herpesvirus 1 ICP22/ICP27 hybrid protein encoded by defective interfering particles associated with persistent infection.
P2860
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P2860
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
@ast
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
@en
type
label
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
@ast
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
@en
prefLabel
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
@ast
Identification and characterization of the ICP22 protein of equine herpesvirus 1.
@en
P2093
P2860
P1433
P1476
Identification and characterization of the ICP22 protein of equine herpesvirus 1
@en
P2093
D J O'Callaghan
G B Caughman
V R Holden
P2860
P304
P407
P577
1994-07-01T00:00:00Z