Herpes simplex virus type 1 DNA replication and gene expression during explant-induced reactivation of latently infected murine sensory ganglia.
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Potential role for luman, the cellular homologue of herpes simplex virus VP16 (alpha gene trans-inducing factor), in herpesvirus latencyThe probability of in vivo reactivation of herpes simplex virus type 1 increases with the number of latently infected neurons in the ganglia.Explant-induced reactivation of herpes simplex virus occurs in neurons expressing nuclear cdk2 and cdk4Dimethyl sulfoxide blocks herpes simplex virus-1 productive infection in vitro acting at different stages with positive cooperativity. Application of micro-array analysis.Laser-capture microdissection: refining estimates of the quantity and distribution of latent herpes simplex virus 1 and varicella-zoster virus DNA in human trigeminal Ganglia at the single-cell level.Towards an understanding of the herpes simplex virus type 1 latency-reactivation cycleEpigenetic regulation of latent HSV-1 gene expression.The quantity of latent viral DNA correlates with the relative rates at which herpes simplex virus types 1 and 2 cause recurrent genital herpes outbreaks.Immunohistochemical analysis of primary sensory neurons latently infected with herpes simplex virus type 1.Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in miceNumerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2.Gene array analysis reveals changes in peripheral nervous system gene expression following stimuli that result in reactivation of latent herpes simplex virus type 1: induction of transcription factor Bcl-3.Modeling HSV-1 Latency in Human Embryonic Stem Cell-Derived Neurons.Spontaneous molecular reactivation of herpes simplex virus type 1 latency in mice.A herpes simplex virus type 1 mutant expressing a baculovirus inhibitor of apoptosis gene in place of latency-associated transcript has a wild-type reactivation phenotype in the mouse.Use of differential display reverse transcription-PCR to reveal cellular changes during stimuli that result in herpes simplex virus type 1 reactivation from latency: upregulation of immediate-early cellular response genes TIS7, interferon, and interA gene capable of blocking apoptosis can substitute for the herpes simplex virus type 1 latency-associated transcript gene and restore wild-type reactivation levelsA mutation in the latency-related gene of bovine herpesvirus 1 disrupts the latency reactivation cycle in calves.Stable cell lines expressing high levels of the herpes simplex virus type 1 LAT are refractory to caspase 3 activation and DNA laddering following cold shock induced apoptosisInfection of cattle with a bovine herpesvirus 1 strain that contains a mutation in the latency-related gene leads to increased apoptosis in trigeminal ganglia during the transition from acute infection to latency.A novel herpes simplex virus type 1 transcript (AL-RNA) antisense to the 5' end of the latency-associated transcript produces a protein in infected rabbits.Herpes simplex virus type 1 and bovine herpesvirus 1 latency.Tissue-specific splicing of the herpes simplex virus type 1 latency-associated transcript (LAT) intron in LAT transgenic miceExperimental investigation of herpes simplex virus latencyQuantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virusA 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation.Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency.Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue culturesComprehensive quantification of herpes simplex virus latency at the single-cell levelThe herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latencyA viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus.Herpes simplex virus genome replication and transcription during induced reactivation in the rabbit eye.Decreased reactivation of a herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) mutant using the in vivo mouse UV-B model of induced reactivation.Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigsIncreased neurovirulence and reactivation of the herpes simplex virus type 1 latency-associated transcript (LAT)-negative mutant dLAT2903 with a disrupted LAT miR-H2History and genomic sequence analysis of the herpes simplex virus 1 KOS and KOS1.1 sub-strains.CTCF occupation of the herpes simplex virus 1 genome is disrupted at early times postreactivation in a transcription-dependent manner.Herpes simplex virus 1 tropism for human sensory ganglion neurons in the severe combined immunodeficiency mouse model of neuropathogenesisMolecular analysis of herpes simplex virus type 1 during epinephrine-induced reactivation of latently infected rabbits in vivo.Effect of the transcription start region of the herpes simplex virus type 1 latency-associated transcript promoter on expression of productively infected neurons in vivo.
P2860
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P2860
Herpes simplex virus type 1 DNA replication and gene expression during explant-induced reactivation of latently infected murine sensory ganglia.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@ast
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@en
type
label
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@ast
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@en
prefLabel
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@ast
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@en
P2093
P2860
P1433
P1476
Herpes simplex virus type 1 DN ...... fected murine sensory ganglia.
@en
P2093
E K Wagner
G B Devi-Rao
J G Stevens
P2860
P304
P407
P577
1994-03-01T00:00:00Z