Major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes from horses with equine infectious anemia virus recognize Env and Gag/PR proteins.
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Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus.Detection and induction of equine infectious anemia virus-specific cytotoxic T-lymphocyte responses by use of recombinant retroviral vectors.Gag protein epitopes recognized by CD4(+) T-helper lymphocytes from equine infectious anemia virus-infected carrier horses.Biological characterization of Rev variation in equine infectious anemia virusLymphocyte proliferation responses induced to broadly reactive Th peptides did not protect against equine infectious anemia virus challengeFailure of low-dose recombinant human IL-2 to support the survival of virus-specific CTL clones infused into severe combined immunodeficient foals: lack of correlation between in vitro activity and in vivo efficacy.Equine infectious anemia virus envelope evolution in vivo during persistent infection progressively increases resistance to in vitro serum antibody neutralization as a dominant phenotype.Maturation of the cellular and humoral immune responses to persistent infection in horses by equine infectious anemia virus is a complex and lengthy process.CTL from EIAV carrier horses with diverse MHC class I alleles recognize epitope clusters in Gag matrix and capsid proteinsEarly detection of dominant Env-specific and subdominant Gag-specific CD8+ lymphocytes in equine infectious anemia virus-infected horses using major histocompatibility complex class I/peptide tetrameric complexes.Immune reconstitution prevents continuous equine infectious anemia virus replication in an Arabian foal with severe combined immunodeficiency: lessons for control of lentiviruses.A single amino acid difference within the alpha-2 domain of two naturally occurring equine MHC class I molecules alters the recognition of Gag and Rev epitopes by equine infectious anemia virus-specific CTL.Evaluation of high functional avidity CTL to Gag epitope clusters in EIAV carrier horsesCloning and large-scale expansion of epitope-specific equine cytotoxic T lymphocytes using an anti-equine CD3 monoclonal antibody and human recombinant IL-2Development and characterization of an equine infectious anemia virus Env-pseudotyped reporter virusViral load and clinical disease enhancement associated with a lentivirus cytotoxic T lymphocyte vaccine regimen.Rhodococcus equi-infected macrophages are recognized and killed by CD8+ T lymphocytes in a major histocompatibility complex class I-unrestricted fashion.Lessons in AIDS vaccine development learned from studies of equine infectious, anemia virus infection and immunity.Gag protein epitopes recognized by ELA-A-restricted cytotoxic T lymphocytes from horses with long-term equine infectious anemia virus infection.Immune responses and viral replication in long-term inapparent carrier ponies inoculated with equine infectious anemia virus.Host range of small-ruminant lentivirus cytopathic variants determined with a selectable caprine arthritis- encephalitis virus pseudotype system.Specific cytotoxic T lymphocytes are involved in in vivo clearance of infectious bronchitis virus.Subpopulations of equine infectious anemia virus Rev coexist in vivo and differ in phenotype.Epitope shifting of gp90-specific cellular immune responses in EIAV-infected ponies.Experimental Rhodococcus equi and equine infectious anemia virus DNA vaccination in adult and neonatal horses: effect of IL-12, dose, and route.Early development of cytotoxic T lymphocytes in neonatal foals following oral inoculation with Rhodococcus equiEnvelope determinants of equine infectious anemia virus vaccine protection and the effects of sequence variation on immune recognition.Identification of Rhodococcus equi lipids recognized by host cytotoxic T lymphocytes.Equine infectious anemia virus resists the antiretroviral activity of equine APOBEC3 proteins through a packaging-independent mechanism.
P2860
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P2860
Major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes from horses with equine infectious anemia virus recognize Env and Gag/PR proteins.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Major histocompatibility compl ...... gnize Env and Gag/PR proteins.
@ast
Major histocompatibility compl ...... gnize Env and Gag/PR proteins.
@en
type
label
Major histocompatibility compl ...... gnize Env and Gag/PR proteins.
@ast
Major histocompatibility compl ...... gnize Env and Gag/PR proteins.
@en
prefLabel
Major histocompatibility compl ...... gnize Env and Gag/PR proteins.
@ast
Major histocompatibility compl ...... gnize Env and Gag/PR proteins.
@en
P2093
P2860
P1433
P1476
Major histocompatibility compl ...... ognize Env and Gag/PR proteins
@en
P2093
A L Brassfield
K I O'Rourke
L E Perryman
T C McGuire
P2860
P304
P407
P577
1994-03-01T00:00:00Z