Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma. - Wikidata - awgldk - TriplyDB

Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

http://www.wikidata.org/entity/Q36631618

about

Pediatric medulloblastoma - update on molecular classification driving targeted therapies EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma Kabuki syndrome: clinical and molecular characteristics Epigenetic dysregulation: a novel pathway of oncogenesis in pediatric brain tumors Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma The H3K27me3 demethylase UTX in normal development and disease.Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation.Whole-exome sequencing defines the mutational landscape of pheochromocytoma and identifies KMT2D as a recurrently mutated gene Overcoming multiple drug resistance mechanisms in medulloblastoma.Deregulated proliferation and differentiation in brain tumors.Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.Genetic and molecular alterations across medulloblastoma subgroups Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups.Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors Role of several histone lysine methyltransferases in tumor development.Mutations in chromatin machinery and pediatric high-grade glioma Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.Role of MYC in Medulloblastoma.Mutational Analysis of Extranodal NK/T-Cell Lymphoma Using Targeted Sequencing with a Comprehensive Cancer Panel Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations.Intertumoral and intratumoral heterogeneity as a barrier for effective treatment of medulloblastoma.The roles of Jumonji-type oxygenases in human disease.RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma.Duration of the pre-diagnostic interval in medulloblastoma is subgroup dependent.The biologic era of childhood medulloblastoma and clues to novel therapies.Examining the impact of gene variants on histone lysine methylation The molecular landscape of pediatric brain tumors in the next-generation sequencing era.Evolving molecular era of childhood medulloblastoma: time to revisit therapy.p53 and Meduloblastoma.An epigenetic gateway to brain tumor cell identity.Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma.SMARCA4/Brg1 coordinates genetic and epigenetic networks underlying Shh-type medulloblastoma development.Viability of D283 medulloblastoma cells treated with a histone deacetylase inhibitor combined with bombesin receptor antagonists.BET bromodomain inhibition of MYC-amplified medulloblastoma.The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma.Advances in Molecular Imaging of Locally Delivered Targeted Therapeutics for Central Nervous System Tumors.

P2860

Q21129295-B59C3220-4317-4CC9-9A92-DBE24BB803A7 Q24338526-D197E626-9575-4AC5-A0E0-B272F8BCB783 Q26778099-4E87B16D-BECC-4323-96BE-77C26CC39C5B Q26864920-778BEEFA-CF7D-44DD-8498-32C52F4373D4 Q33633473-DBEFC9C1-41EB-471F-8752-AB2477EADB8F Q33751426-FE2BBD07-468E-48EA-9A9D-38A6E344E78C Q33779153-78E30B4C-B08C-434E-866F-A7DAEB03D7AA Q34363432-3E770386-3831-47FD-8592-F65EBD93B009 Q34385576-2454C9F0-8A24-4B6B-BB0A-955F684A69FD Q34478820-CB229344-4E4C-46C2-BE2C-0EA3F4FEB0B7 Q34500602-D27C084C-E322-40AB-9B8C-450C11F72466 Q34859989-36423C98-D734-4E10-915C-97958E973EE7 Q35135650-9AAEC764-397B-48A4-BE65-8634F426D537 Q35246513-B0FF0B27-7270-4B88-A952-A0ACBB6229DF Q36142459-B228D4C0-0BCF-4C62-97C5-775F4C1A7607 Q36288376-CE1567B2-40C6-4DBD-A48A-2F77B186185A Q36480084-2FBCF570-9598-4835-B6FD-1C18BDCB9279 Q36639797-A085E542-FA63-497D-A30F-7ED124518038 Q36716785-74DC687C-6367-449D-8163-FFD948815C21 Q36981245-C7D64091-9BD5-40E9-9596-4C1DB52A2763 Q37004219-FA10BD25-5E7C-4E90-872E-8993E238F57C Q37256443-3F00F03D-2589-455A-8797-CEFA43F7C308 Q37324841-552C035F-A260-4C8B-906E-B5ACB37172C3 Q37529593-88663B15-CA2E-4B59-BF6F-2B99E4FC92DA Q38120467-141E54C2-B39B-4E2B-9D1E-2768BC963C3B Q38192028-5733C52D-F3FE-4FE7-A4C4-E8243B1A10DA Q38194436-3CE9E903-BFA6-4E0B-A653-C35FCD25116A Q38194990-38D3118E-6C94-4E5B-BE33-06D74BB05808 Q38206276-B16276E9-C309-4974-899F-A4CFEBBBD942 Q38214535-E4EB9D50-01BA-4D8C-8D99-71C89D438B8A Q38231122-22936376-B930-4F13-AA36-C87E74F7A074 Q38652681-9473979D-CF63-4CAB-8EB5-52D0AE648D2C Q38673795-A7EC99DC-4801-4C06-9AA4-B9DFAFD70426 Q38682159-BA71DDBB-23B5-4061-B1B1-47DC87B9CF6C Q38714341-BEA0C323-A51A-49EB-83DF-35B5D85848F9 Q38734099-CD6B68A9-6B71-457D-AA37-951777EDB301 Q38817974-C75A9ADE-EE3B-43AF-BA89-D20DE3CF30E2 Q39050679-C261FF05-1ACC-443B-979F-BCF0FC2238AB Q39061338-6ED3915F-19B1-445B-B0C6-72B8468EC261 Q39139224-837EF644-5D36-4F12-B6F2-9F385D50FB65

P2860

Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

http://www.wikidata.org/entity/Q36631618

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Aberrant patterns of H3K4 and ...... subgroups in medulloblastoma.

@ast

Aberrant patterns of H3K4 and ...... subgroups in medulloblastoma.

@en

type

label

Aberrant patterns of H3K4 and ...... subgroups in medulloblastoma.

@ast

Aberrant patterns of H3K4 and ...... subgroups in medulloblastoma.

@en

prefLabel

Aberrant patterns of H3K4 and ...... subgroups in medulloblastoma.

@ast

Aberrant patterns of H3K4 and ...... subgroups in medulloblastoma.

@en

P1433

Q36631618-107023A1-1A34-4EAB-BF69-69F3109F039C

P1476

Q36631618-03E6AB64-7CCA-4895-BD82-50CF8F891032

P2093

Q36631618-06D315BF-38A1-4654-A6AA-278A14CCFF5E

Q36631618-07BFB031-F2F0-4646-9258-56ECDAF1AE4F

Q36631618-0E114C14-EC5E-4E1A-AEB2-E0CA631FBA1E

Q36631618-131B17E5-4D1F-4521-94AC-E55DAF2EBAE0

Q36631618-1EBD5074-5094-4E2E-945F-4E25EA249A2A

Q36631618-2164569D-76C3-4456-B091-1136D44F6CA3

Q36631618-22EEB29C-1E6D-4236-8630-54B9FD43E50E

Q36631618-3A7AE5EA-E3B9-4F23-9E2B-C7F1329D9FD4

Q36631618-3D709763-1B1B-49DA-96D7-FE2B469E44ED

Q36631618-427C52D6-9B5E-4B49-8906-07C750293541

P2860

Q36631618-0AA4A00B-FC83-4045-91BD-024D07F81BFB

Q36631618-0F114379-1EED-4232-BB1B-7C539E6853E3

Q36631618-32AAEBB1-E51D-4E67-9085-BBCFC25C15A0

Q36631618-34EB44EB-7268-4294-8F26-36C50FD5BB79

Q36631618-3BA38085-A3B0-4A6F-88E6-825B5EF78A75

Q36631618-3F0B887E-0C62-46D1-8C22-415C5893BE99

Q36631618-4CEB7D16-DD6A-4FF8-A735-548D3284043E

Q36631618-61CB6A0C-E7DE-400E-B494-BF29B39238D5

Q36631618-7B1B0430-94DC-4AB2-A21C-26C42C8D09E0

Q36631618-7C90C77A-5070-4E3E-9EC4-D6BFE7119B68

P2888

Q36631618-0274C434-A234-4163-97CD-76ECB7190B4C

P304

Q36631618-B0A9ED4C-3043-44EA-AAC1-B7232EDF1101

P31

Q36631618-25AE1E9E-6C81-468C-AA93-FA010DDA3B7A

P356

Q36631618-2D729792-EB47-4A5E-B62D-110CBE8F0CEE

P433

Q36631618-A82F2DE9-19DD-42AE-8588-982B34B5C6E2

P478

Q36631618-DB561E68-4F97-4BA3-AD69-CF3FD27E97AA

P50

Q36631618-0C9AC2A2-0B16-404F-B849-B8C0A082CF53

Q36631618-0FD77740-18DB-432D-9F95-69C5F7065EB7

Q36631618-37C3D322-7B3B-4380-BFDE-5F8692BC1411

Q36631618-56BA1CA2-4E92-4471-929F-9749E6BC4F94

Q36631618-628134CD-EEF4-4C98-91A6-4C5EDCCB1658

Q36631618-B000A54E-5F9E-4CF5-BD29-5094A508399A

Q36631618-C80A59C0-C72C-448A-A674-5B5B0681E42F

Q36631618-D33DDA8C-9E60-42EC-8BC8-35D48AD07578

P577

Q36631618-294931E1-64E5-4916-A814-5E7B76C49D1E

P698

Q36631618-830CF392-45A6-47F1-BEE9-F9CA1C38E546

P921

Q36631618-4D9A5DE1-68AD-4B61-A5BD-C1F5E54F7403

P932

Q36631618-3A436278-1F2D-4F37-B09C-909E01F9571D

P356

S00401-012-1070-9

P1433

Acta Neuropathologica

P1476

Aberrant patterns of H3K4 and ...... s subgroups in medulloblastoma

@en

P2093

A Sorana Morrissy

http://www.w3.org/2001/XMLSchema#string

Adi Rolider

http://www.w3.org/2001/XMLSchema#string

Adrian M Dubuc

http://www.w3.org/2001/XMLSchema#string

Alexander Unterberger

http://www.w3.org/2001/XMLSchema#string

Andrey Korshunov

http://www.w3.org/2001/XMLSchema#string

Cynthia Hawkins

http://www.w3.org/2001/XMLSchema#string

David T W Jones

http://www.w3.org/2001/XMLSchema#string

Hendrik Witt

http://www.w3.org/2001/XMLSchema#string

James T Rutka

http://www.w3.org/2001/XMLSchema#string

John Peacock

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular subgroups of medulloblastoma: the current consensus

Dissecting the genomic complexity underlying medulloblastoma

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour Committee

Genome regulation by polycomb and trithorax proteins

The genetic landscape of the childhood cancer medulloblastoma

Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse development

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

P2888

s00401-012-1070-9

P304

373-384

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S00401-012-1070-9

http://www.w3.org/2001/XMLSchema#string

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

125

http://www.w3.org/2001/XMLSchema#string

P50

William A Weiss

Stefan M Pfister

Vijay Ramaswamy

Charles G Eberhart

P577

2012-11-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23184418

http://www.w3.org/2001/XMLSchema#string

P921

medulloblastoma

P932

3580007

http://www.w3.org/2001/XMLSchema#string