Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.
about
A novel TGFβ modulator that uncouples R-Smad/I-Smad-mediated negative feedback from R-Smad/ligand-driven positive feedbackTranscription factor regulation of pancreatic organogenesis, differentiation and maturationIslet-1 Is essential for pancreatic β-cell function.Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass.Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthoodDynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cellsSSBP3 Interacts With Islet-1 and Ldb1 to Impact Pancreatic β-Cell Target Genes.Endocrine pancreatic development: impact of obesity and diet.Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.Gene regulatory networks governing pancreas development.Insulin-like genes in ascidians: findings in Ciona and hypotheses on the evolutionary origins of the pancreasImpact of Pdx1-associated chromatin modifiers on islet β-cells.LDB1 Regulates Energy Homeostasis During Diet-Induced Obesity.Cell type and tissue specific function of islet genes in zebrafish pancreas development.Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts.Connective tissue growth factor is critical for proper β-cell function and pregnancy-induced β-cell hyperplasia in adult miceIsl1 Controls Patterning and Mineralization of Enamel in the Continuously Renewing Mouse Incisor.Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10, and Wnt5a.Chewing the Fat: A Metabolic Role for Ldb1 Beyond the Pancreas?
P2860
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P2860
Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Islet α-, β-, and δ-cell devel ...... islet-1 transcription factor.
@ast
Islet α-, β-, and δ-cell devel ...... islet-1 transcription factor.
@en
type
label
Islet α-, β-, and δ-cell devel ...... islet-1 transcription factor.
@ast
Islet α-, β-, and δ-cell devel ...... islet-1 transcription factor.
@en
prefLabel
Islet α-, β-, and δ-cell devel ...... islet-1 transcription factor.
@ast
Islet α-, β-, and δ-cell devel ...... islet-1 transcription factor.
@en
P2093
P2860
P356
P1433
P1476
Islet α-, β-, and δ-cell devel ...... e islet-1 transcription factor
@en
P2093
Benjamin Ediger
Catherine Lee May
Crystal Wilcox
Heiner Westphal
Mark Ferreira
Roland Stein
Shilpy Dixit
Tsadok Cohen
P2860
P304
P356
10.2337/DB12-0952
P407
P577
2012-11-27T00:00:00Z