The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
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FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3FANCE: the link between Fanconi anaemia complex assembly and activityFanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complexA physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCAHuman alpha spectrin II and the Fanconi anemia proteins FANCA and FANCC interact to form a nuclear complexThe Fanconi anaemia/BRCA pathwayA novel ubiquitin ligase is deficient in Fanconi anemiaThe Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchangeFanconi anemia protein complex is a novel target of the IKK signalsomeThe Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartmentsOxidative stress/damage induces multimerization and interaction of Fanconi anemia proteinsFANCC, FANCE, and FANCD2 form a ternary complex essential to the integrity of the Fanconi anemia DNA damage response pathwayHES1 is a novel interactor of the Fanconi anemia core complexFanconi anemia proteins localize to chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner.Phosphorylation of fanconi anemia (FA) complementation group G protein, FANCG, at serine 7 is important for function of the FA pathway.FANCG is phosphorylated at serines 383 and 387 during mitosisATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway functionDeficient DNA end joining activity in extracts from fanconi anemia fibroblasts.Fanconi anemia proteins and their interacting partners: a molecular puzzleFanconi anemia proteins stabilize replication forks.Knockdown of mu-calpain in Fanconi anemia, FA-A, cells by siRNA restores alphaII spectrin levels and corrects chromosomal instability and defective DNA interstrand cross-link repair.The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector.Congenital bone marrow failure syndromes.The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.Erythropoiesis: Current Clinical Practice: Advances in the Genetics and Biology of Fanconi Anaemia.Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repairThe Fanconi anemia pathway and ICL repair: implications for cancer therapy.A case report and literature review of Fanconi Anemia (FA) diagnosed by genetic testing.Evidence for subcomplexes in the Fanconi anemia pathway.Natural gene therapy in monozygotic twins with Fanconi anemiaUbiquitylation and the Fanconi anemia pathway.Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance.Reconstruction of a functional human gene network, with an application for prioritizing positional candidate genes.Complementation analysis in Fanconi anemia: assignment of the reference FA-H patient to group ADeficient regulation of DNA double-strand break repair in Fanconi anemia fibroblasts.Aberrant Fanconi anaemia protein profiles in acute myeloid leukaemia cells
P2860
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P2860
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@ast
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@en
type
label
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@ast
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@en
prefLabel
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@ast
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@en
P2093
P2860
P356
P1476
The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation.
@en
P2093
A D D'Andrea
G M Kupfer
T Yamashita
P2860
P304
13085-13090
P356
10.1073/PNAS.95.22.13085
P407
P577
1998-10-01T00:00:00Z