Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences.
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Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sitesConduction abnormalities and ventricular arrhythmogenesis: The roles of sodium channels and gap junctionsThe role of late I Na in development of cardiac arrhythmiasThe late Na+ current--origin and pathophysiological relevanceNa+ channel function, regulation, structure, trafficking and sequestrationNew therapeutic targets in cardiology: arrhythmias and Ca2+/calmodulin-dependent kinase II (CaMKII)Role of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death.Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasVoltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytesCardiac Na Channels: Structure to FunctionToward a hierarchy of mechanisms in CaMKII-mediated arrhythmia.Electrical remodeling in the failing heart.Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure.Location, location, regulation: a novel role for β-spectrin in the heart.Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling.Calpain inhibition reduces amplitude and accelerates decay of the late sodium current in ventricular myocytes from dogs with chronic heart failurePost-transcriptional silencing of SCN1B and SCN2B genes modulates late sodium current in cardiac myocytes from normal dogs and dogs with chronic heart failure.Mechanisms of ventricular arrhythmias: a dynamical systems-based perspective.Basic science of cardiac resynchronization therapy: molecular and electrophysiological mechanismsPost-translational modifications of voltage-gated sodium channels in chronic pain syndromesExcavatolide B Modulates the Electrophysiological Characteristics and Calcium Homeostasis of Atrial Myocytes.CaMKII-dependent activation of late INa contributes to cellular arrhythmia in a model of the cardiac myocyte.Mass spectrometry-based identification of native cardiac Nav1.5 channel α subunit phosphorylation sites.Molecular identity of the late sodium current in adult dog cardiomyocytes identified by Nav1.5 antisense inhibition.Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart.Electrophysiological consequences of dyssynchronous heart failure and its restoration by resynchronization therapy.Pathophysiology of the cardiac late Na current and its potential as a drug target.Late Na+ current produced by human cardiac Na+ channel isoform Nav1.5 is modulated by its beta1 subunit.Calcium/calmodulin-dependent kinase II regulation of cardiac ion channels.NCX is an important determinant for premature ventricular activity in a drug-induced model of Andersen-Tawil syndrome.CaMKII in myocardial hypertrophy and heart failureCaMKII in the cardiovascular system: sensing redox states.Electrical remodeling in dyssynchrony and resynchronization.Late sodium current inhibition in acquired and inherited ventricular (dys)function and arrhythmias.A Memory Molecule, Ca(2+)/Calmodulin-Dependent Protein Kinase II and Redox Stress; Key Factors for Arrhythmias in a Diseased Heart.The late sodium current in heart failure: pathophysiology and clinical relevance.The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine.Potential new mechanisms of pro-arrhythmia in arrhythmogenic cardiomyopathy: focus on calcium sensitive pathways
P2860
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P2860
Modulation of late sodium current by Ca2+, calmodulin, and CaMKII in normal and failing dog cardiomyocytes: similarities and differences.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Modulation of late sodium curr ...... similarities and differences.
@ast
Modulation of late sodium curr ...... similarities and differences.
@en
type
label
Modulation of late sodium curr ...... similarities and differences.
@ast
Modulation of late sodium curr ...... similarities and differences.
@en
prefLabel
Modulation of late sodium curr ...... similarities and differences.
@ast
Modulation of late sodium curr ...... similarities and differences.
@en
P2093
P2860
P1476
Modulation of late sodium curr ...... similarities and differences.
@en
P2093
Albertas Undrovinas
Hani N Sabbah
Nidas A Undrovinas
Victor A Maltsev
Vitaliy Reznikov
P2860
P304
P356
10.1152/AJPHEART.00484.2007
P577
2008-01-18T00:00:00Z