A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin. - Wikidata - awgldk - TriplyDB

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.

A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.

http://www.wikidata.org/entity/Q36646385

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KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection DNA minicircles clarify the specific role of DNA structure on retroviral integration A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain Retroviral DNA Integration Structural basis for spumavirus GAG tethering to chromatin A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration.HIV-1 capsid is involved in post-nuclear entry steps The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency.The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes.What Integration Sites Tell Us about HIV Persistence Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration.Cyclophilin A potentiates TRIM5α inhibition of HIV-1 nuclear import without promoting TRIM5α binding to the viral capsid.Imaging HIV-1 Genomic DNA from Entry through Productive Infection Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein.Connecting HIV-1 integration and transcription: a step toward new treatments.Integration site selection by retroviruses and transposable elements in eukaryotes.Nuclear landscape of HIV-1 infection and integration.Retroviral integrase protein and intasome nucleoprotein complex structures.Capsid-Dependent Host Factors in HIV-1 Infection.Role of Innate Genes in HIV Replication.Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro.N-terminally truncated POM121C inhibits HIV-1 replication.Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes.Effects of Inner Nuclear Membrane Proteins SUN1/UNC-84A and SUN2/UNC-84B on the Early Steps of HIV-1 Infection.Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation.Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.The HIV-1 integrase-LEDGF allosteric inhibitor MUT-A: resistance profile, impairment of virus maturation and infectivity but without influence on RNA packaging or virus immunoreactivity.Host factors that promote retrotransposon integration are similar in distantly related eukaryotes.Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails.Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation.Cellular and molecular mechanisms of HIV-1 integration targeting.Truncated CPSF6 forms higher order complexes that bind and disrupt HIV-1 capsid.Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors.Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T Cells.Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis.Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis.Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing Cells

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A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin.

http://www.wikidata.org/entity/Q36646385

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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A critical role for alternativ ...... criptionally active chromatin.

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A critical role for alternativ ...... criptionally active chromatin.

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Proceedings of the National Academy of Sciences of the United States of America

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A critical role for alternativ ...... criptionally active chromatin.

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Alan N Engelman

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Eric M Poeschla

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Erik Serrao

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Gregory A Sowd

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Hao Wang

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Hind J Fadel

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Weifeng Wang

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P2860

Association of polyadenylation cleavage factor I with U1 snRNP.

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency

An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries

LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes

Multiplex genome engineering using CRISPR/Cas systems

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3'-end processing of animal histone mRNAs

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration

Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

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113

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26858452

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4776470

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