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Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasionRho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapyCell-cell and cell-matrix dynamics in intraperitoneal cancer metastasisRegulation of ROCK activity in cancerVascular anomalies: from genetics toward models for therapeutic trialsRKI-1447 Is a Potent Inhibitor of the Rho-Associated ROCK Kinases with Anti-Invasive and Antitumor Activities in Breast CancerRas superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasionThe planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturationThe Tumor Suppressor, p190RhoGAP, Differentially Initiates Apoptosis and Confers Docetaxel Sensitivity to Breast Cancer Cells.ABL2/ARG tyrosine kinase mediates SEMA3F-induced RhoA inactivation and cytoskeleton collapse in human glioma cells.Inhibition of Rho-associated kinases disturbs the collective cell migration of stratified TE-10 cellsDerivation and osmotolerance characterization of three immortalized tilapia (Oreochromis mossambicus) cell lines.Targeting protein kinases in central nervous system disordersHigh-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules.Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency.Rho kinase proteins display aberrant upregulation in vascular tumors and contribute to vascular tumor growth.Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions.Simvastatin improves clinical scores in a rabbit multiple infarct ischemic stroke model: synergism with a ROCK inhibitor but not the thrombolytic tissue plasminogen activator.Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Rho-ROCK-myosin signaling mediates membrane type 1 matrix metalloproteinase-induced cellular aggregation of keratinocytes.ROCK1 plays an essential role in the transition from cardiac hypertrophy to failure in mice.LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells.Statins and myocardial remodelling: cell and molecular pathways.Ser1333 phosphorylation indicates ROCKI activation.Rho/ROCK signaling in motility and metastasis of gastric cancerEffects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits.Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis.The effects of Rho-associated kinase inhibitor Y-27632 on primary human corneal endothelial cells propagated using a dual media approachRho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem CellsRecent Patents on Emerging Therapeutics for the Treatment of Glaucoma, Age Related Macular Degeneration and Uveitis.Role of the Rho pathway in regulating valvular interstitial cell phenotype and nodule formation.Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism.ROCK inhibitor enhances adhesion and wound healing of human corneal endothelial cellsTargeting Rho-GTPases in immune cell migration and inflammation.Cryopreservation of Human Stem Cells for Clinical Application: A ReviewROCK1 is a potential combinatorial drug target for BRAF mutant melanomaActivation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease.The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Applications for ROCK kinase inhibition
@ast
Applications for ROCK kinase inhibition
@en
type
label
Applications for ROCK kinase inhibition
@ast
Applications for ROCK kinase inhibition
@en
prefLabel
Applications for ROCK kinase inhibition
@ast
Applications for ROCK kinase inhibition
@en
P2860
P1476
Applications for ROCK kinase inhibition
@en
P2860
P304
P356
10.1016/J.CEB.2008.01.002
P577
2008-02-20T00:00:00Z