Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly
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Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65)Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicingFunctional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNAThe pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling proteinHerpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic stepEvidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammalsPartial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome assemblyA novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.Association of U2 snRNP with the spliceosomal complex EDomains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formationSpecific protein-protein interactions between the essential mammalian spliceosome-associated proteins SAP 61 and SAP 114A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reactionA T to G mutation in the polypyrimidine tract of the second intron of the human beta-globin gene reduces in vitro splicing efficiency: evidence for an increased hnRNP C interactionWW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motifHIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicingHuman immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNPSolution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motifConservation of structure and subunit interactions in yeast homologues of splicing factor 3b (SF3b) subunits.Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes.The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulationA functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in DrosophilaAn exonic splicing silencer is involved in the regulated splicing of glucose 6-phosphate dehydrogenase mRNAAltered levels of the Drosophila HRB87F/hrp36 hnRNP protein have limited effects on alternative splicing in vivo.The exon splicing silencer in human immunodeficiency virus type 1 Tat exon 3 is bipartite and acts early in spliceosome assembly.The SR splicing factors ASF/SF2 and SC35 have antagonistic effects on intronic enhancer-dependent splicing of the beta-tropomyosin alternative exon 6AMultiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.Characterization of human RNA splice signals by iterative functional selection of splice sites.3' splice site recognition in nematode trans-splicing involves enhancer-dependent recruitment of U2 snRNPSequential recognition of the pre-mRNA branch point by U2AF65 and a novel spliceosome-associated 28-kDa proteinThe nuclear matrix phosphoprotein p255 associates with splicing complexes as part of the [U4/U6.U5] tri-snRNP particle.Members of a family of proteins (the RD family) detected by a U1 70K monoclonal antibody are present in spliceosomal complexes.Three recognition events at the branch-site adenine.Selection of the bovine papillomavirus type 1 nucleotide 3225 3' splice site is regulated through an exonic splicing enhancer and its juxtaposed exonic splicing suppressorAccumulation of a novel spliceosomal complex on pre-mRNAs containing branch site mutations.Invariant U2 RNA sequences bordering the branchpoint recognition region are essential for interaction with yeast SF3a and SF3b subunits.A minimal spliceosomal complex A recognizes the branch site and polypyrimidine tract.SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complexMolecular characterization of a novel, widespread nuclear protein that colocalizes with spliceosome components.
P2860
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P2860
Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assembly
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Direct interactions between pr ...... ns during spliceosome assembly
@ast
Direct interactions between pr ...... ns during spliceosome assembly
@en
type
label
Direct interactions between pr ...... ns during spliceosome assembly
@ast
Direct interactions between pr ...... ns during spliceosome assembly
@en
prefLabel
Direct interactions between pr ...... ns during spliceosome assembly
@ast
Direct interactions between pr ...... ns during spliceosome assembly
@en
P2860
P356
P1476
Direct interactions between pr ...... ns during spliceosome assembly
@en
P2093
P2860
P304
P356
10.1128/MCB.14.5.2994
P407
P577
1994-05-01T00:00:00Z