First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer
about
X-ray Scattering Studies of Protein Structural Dynamics.Domain Movements upon Activation of Phenylalanine Hydroxylase Characterized by Crystallography and Chromatography-Coupled Small-Angle X-ray Scattering.Substituting Tyr138 in the active site loop of human phenylalanine hydroxylase affects catalysis and substrate activation.Genetics of Phenylketonuria: Then and Now.Tyrosine and tryptophan hydroxylases as therapeutic targets in human disease.Stable preparations of tyrosine hydroxylase provide the solution structure of the full-length enzyme.Structural basis for ligand-dependent dimerization of phenylalanine hydroxylase regulatory domain.PKU mutation p.G46S prevents the stereospecific binding of l-phenylalanine to the dimer of human phenylalanine hydroxylase regulatory domain.
P2860
Q30101114-3B07AC2B-0696-4F42-BDE0-E77B00495875Q36977345-7F32E817-6B25-43CE-BF38-CDDFDA4E53DFQ38691976-212E73F9-96DA-40C8-95F0-3EDAB98D0151Q38751728-7A2A7345-4A0B-495C-A492-0F3908DF0ECAQ39038494-7EC94D11-F8CC-4BE1-95C6-AAA15405DC7CQ39556136-2F72EA6B-C71E-43B8-A15F-305E707518A1Q39859787-54A2F079-0E99-4F45-B04E-C0450E59B3C2Q42128696-1FC9FCCC-DD81-416B-8801-8C7FE49456EE
P2860
First structure of full-length mammalian phenylalanine hydroxylase reveals the architecture of an autoinhibited tetramer
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
First structure of full-length ...... e of an autoinhibited tetramer
@ast
First structure of full-length ...... e of an autoinhibited tetramer
@en
type
label
First structure of full-length ...... e of an autoinhibited tetramer
@ast
First structure of full-length ...... e of an autoinhibited tetramer
@en
prefLabel
First structure of full-length ...... e of an autoinhibited tetramer
@ast
First structure of full-length ...... e of an autoinhibited tetramer
@en
P2093
P2860
P356
P1476
First structure of full-length ...... e of an autoinhibited tetramer
@en
P2093
Annie Héroux
Eileen K Jaffe
Emilia C Arturo
Kushol Gupta
Linda Stith
Patrick J Loll
Penelope J Cross
P2860
P304
P356
10.1073/PNAS.1516967113
P407
P577
2016-02-16T00:00:00Z