A simple model system for age-dependent DNA damage and cancer
about
De novo origination of a new protein-coding gene in Saccharomyces cerevisiaeGrowth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humansReplicative and chronological aging in Saccharomyces cerevisiae.Growth conditions that increase or decrease lifespan in Saccharomyces cerevisiae lead to corresponding decreases or increases in rates of interstitial deletions and non-reciprocal translocationsGenomic instability is associated with natural life span variation in Saccharomyces cerevisiae.Comparative analyses of time-course gene expression profiles of the long-lived sch9Delta mutant.Calorie restriction and cancer prevention: metabolic and molecular mechanisms.Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic indexCharacterization of low molecular weight chemical fractions of dry bean (Phaseolus vulgaris) for bioactivity using Caenorhabditis elegans longevity and metabolite fingerprinting.Network reconstruction reveals new links between aging and calorie restriction in yeast.Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity.Extension of Saccharomyces paradoxus chronological lifespan by retrotransposons in certain media conditions is associated with changes in reactive oxygen species.Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.Combining magnetic sorting of mother cells and fluctuation tests to analyze genome instability during mitotic cell aging in Saccharomyces cerevisiae.Retrotransposition is associated with genome instability during chronological aging.Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system.Checkpoint kinase phosphorylation in response to endogenous oxidative DNA damage in repair-deficient stationary-phase Saccharomyces cerevisiaeOncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism.A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: decrease in mitochondrial DNA repair activity during ageing.Chronological aging in Saccharomyces cerevisiae.Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae.Molecular biomarkers for chronological age in animal ecology.Dietary restriction and lifespan: Lessons from invertebrate models.Studying age-dependent genomic instability using the S. cerevisiae chronological lifespan model.Assessing chronological aging in Saccharomyces cerevisiae.Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension.pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast.Hypothesis: is yeast a clock model to study the onset of humans aging phenotypes?Oxidative stress during aging of the yeast in a stationary culture and its attenuation by antioxidants.Inositol pyrophosphates modulate hydrogen peroxide signalling.High reactive oxygen species levels are detected at the end of the chronological life span of translocant yeast cells.What is the meaning of 'A compound is carcinogenic'?
P2860
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P2860
A simple model system for age-dependent DNA damage and cancer
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A simple model system for age-dependent DNA damage and cancer
@ast
A simple model system for age-dependent DNA damage and cancer
@en
type
label
A simple model system for age-dependent DNA damage and cancer
@ast
A simple model system for age-dependent DNA damage and cancer
@en
prefLabel
A simple model system for age-dependent DNA damage and cancer
@ast
A simple model system for age-dependent DNA damage and cancer
@en
P2093
P2860
P1476
A simple model system for age-dependent DNA damage and cancer
@en
P2093
P2860
P356
10.1016/J.MAD.2006.11.009
P577
2006-11-21T00:00:00Z