Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.
about
I-SceI-induced gene replacement at a natural locus in embryonic stem cellsAnimal models of hemophiliaA mouse model for beta 0-thalassemiaA gene-targeting approach identifies a function for the first intron in expression of the alpha1(I) collagen gene.Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells.A human embryonic hemoglobin inhibits Hb S polymerization in vitro and restores a normal phenotype to mouse models of sickle cell disease.The panoply of animal models for sickle cell anaemia.Dynamic posttranscriptional regulation of epsilon-globin gene expression in vivo.Chemoselection of allogeneic HSC after murine neonatal transplantation without myeloablation or post-transplant immunosuppression.Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb betas-globin yeast artificial chromosome: A mouse model of sickle cell anemiaA viable mouse model of factor X deficiency provides evidence for maternal transfer of factor XSingle-copy transgenic mice with chosen-site integration.Pre-selection of integration sites imparts repeatable transgene expression.Introduction of precise alterations into the mouse genome with high efficiency by stable tag-exchange gene targeting: implications for gene targeting in ES cells.Gene modification via "plug and socket" gene targeting.Double replacement gene targeting for the production of a series of mouse strains with different prion protein gene alterations.The molecular basis of multiple vector insertion by gene targeting in mammalian cellsA post-transcriptional process contributes to efficient gamma-globin gene silencing in definitive erythroid cells.High-throughput knock-in coupling gene targeting with the HPRT minigene and Cre-mediated recombination.
P2860
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P2860
Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Deletion and replacement of th ...... " repeated targeting strategy.
@ast
Deletion and replacement of th ...... " repeated targeting strategy.
@en
type
label
Deletion and replacement of th ...... " repeated targeting strategy.
@ast
Deletion and replacement of th ...... " repeated targeting strategy.
@en
prefLabel
Deletion and replacement of th ...... " repeated targeting strategy.
@ast
Deletion and replacement of th ...... " repeated targeting strategy.
@en
P2093
P2860
P356
P1476
Deletion and replacement of th ...... " repeated targeting strategy.
@en
P2093
P2860
P304
P356
10.1128/MCB.14.10.6936
P407
P577
1994-10-01T00:00:00Z