The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection
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MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis2-hydroxy arachidonic acid: a new non-steroidal anti-inflammatory drugTriterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease.Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic interventionEffect of prolonged exposure to diesel engine exhaust on proinflammatory markers in different regions of the rat brainBardoxolone methyl (CDDO-Me) as a therapeutic agent: an update on its pharmacokinetic and pharmacodynamic properties.Oleanolic Acid enhances the beneficial effects of preconditioning on PC12 cells.Psychological stress in adolescent and adult mice increases neuroinflammation and attenuates the response to LPS challenge.Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling.Natural triterpenes modulate immune-inflammatory markers of experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosisSynthetic oleanane triterpenoids: multifunctional drugs with a broad range of applications for prevention and treatment of chronic disease.RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells.Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.Human amnion epithelial cells rescue cell death via immunomodulation of microglia in a mouse model of perinatal brain injuryAnti-neuroinflammatory agents for the treatment of Alzheimer's disease.Significance of NF-κB as a pivotal therapeutic target in the neurodegenerative pathologies of Alzheimer's disease and multiple sclerosis.Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.Microglial phenotypes in Parkinson's disease and animal models of the disease.RNF11 modulates microglia activation through NF-κB signalling cascade.Regulation of microglia effector functions by tumor necrosis factor signaling.Synthetic triterpenoid CDDO derivatives modulate cytoprotective or immunological properties in astrocytes, neurons, and microglia.The degenerating substantia nigra as a susceptible region for gene transfer-mediated inflammation.Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a(-/-) mice.Anti-inflammatory efficacy of dexamethasone and Nrf2 activators in the CNS using brain slices as a model of acute injury.Characterization and Isolation of Mouse Primary Microglia by Density Gradient Centrifugation.
P2860
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P2860
The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@ast
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@en
type
label
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@ast
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@en
prefLabel
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@ast
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@en
P2093
P2860
P921
P356
P1476
The synthetic triterpenoid CDD ...... s dopaminergic neuroprotection
@en
P2093
Melissa K McCoy
Michael B Sporn
Thi A Tran
P2860
P2888
P356
10.1186/1742-2094-5-14
P577
2008-05-12T00:00:00Z
P5875
P6179
1053653443