Hypoxia-inducible factors: central regulators of the tumor phenotype. - Wikidata - awgldk - TriplyDB

Hypoxia-inducible factors: central regulators of the tumor phenotype.

Hypoxia-inducible factors: central regulators of the tumor phenotype.

http://www.wikidata.org/entity/Q36701590

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Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation Erythrocytosis-associated HIF-2alpha mutations demonstrate a critical role for residues C-terminal to the hydroxylacceptor proline EAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300 mTOR inhibitors in advanced renal cell carcinoma State of the science: an update on renal cell carcinoma Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma A gain-of-function mutation in the HIF2A gene in familial erythrocytosis AKT/PKB signaling: navigating downstream Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1 Prognostic Significance of Hypoxia-Inducible Factor Expression in Renal Cell Carcinoma: A PRISMA-compliant Systematic Review and Meta-Analysis Circulating biomarkers in advanced renal cell carcinoma: clinical applications Regulating the ARNT/TACC3 Axis: Multiple Approaches to Manipulating Protein/Protein Interactions with Small Molecules Arsenite-induced pseudo-hypoxia results in loss of anchorage-dependent growth in BEAS-2B pulmonary epithelial cells Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytes Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion A comparison of Ku0063794, a dual mTORC1 and mTORC2 inhibitor, and temsirolimus in preclinical renal cell carcinoma models Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice The requirement of c-Jun N-terminal kinase 2 in regulation of hypoxia-inducing factor-1α mRNA stability Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs.Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing.Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells.Meta-analysis of archived DNA microarrays identifies genes regulated by hypoxia and involved in a metastatic phenotype in cancer cells Interleukin-1β promotes hypoxia-induced apoptosis of glioblastoma cells by inhibiting hypoxia-inducible factor-1 mediated adrenomedullin production Estrogen rapidly activates the PI3K/AKT pathway and hypoxia-inducible factor 1 and induces vascular endothelial growth factor A expression in luminal epithelial cells of the rat uterus.Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection.Erythrocytosis associated with a novel missense mutation in the HIF2A gene.The role of hypoxia on the acquisition of epithelial-mesenchymal transition and cancer stemness: a possible link to epigenetic regulation Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo.Renal cell carcinoma: where will the state-of-the-art lead us?YLT192, a novel, orally active bioavailable inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy in preclinical models HIF-2alpha deletion promotes Kras-driven lung tumor development.Aryl hydrocarbon nuclear translocator (hypoxia inducible factor 1beta) activity is required more during early than late tumor growth Real-time determination of intracellular oxygen in bacteria using a genetically encoded FRET-based biosensor Solid tumors associated with multiple endocrine neoplasias.SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.Myc, mondo, and metabolism Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells.

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

http://www.wikidata.org/entity/Q36701590

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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J.GDE.2006.12.006

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Current Opinion in Genetics & Development

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Hypoxia-inducible factors: central regulators of the tumor phenotype.

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John D Gordan

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M Celeste Simon

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P2860

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

Identification of novel VHL target genes and relationship to hypoxic response pathways

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

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