Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
about
Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHLSelective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathwaysAdenosine and hypoxia-inducible factor signaling in intestinal injury and recoveryHypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?HIF hydroxylase pathways in cardiovascular physiology and medicineHypoxia-mediated regulation of macrophage functions in pathophysiologyHypoxia: an alarm signal during intestinal inflammationMolecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseasesHIF prolyl hydroxylase inhibitors for anemiaHearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injuryThe ubiquitin ligase Siah2 and the hypoxia response.Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase.The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolismChronic opioids regulate KATP channel subunit Kir6.2 and carbonic anhydrase I and II expression in rat adrenal chromaffin cells via HIF-2α and protein kinase AGlobal analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death.Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibilityRoles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.NGF activation of TrkA induces vascular endothelial growth factor expression via induction of hypoxia-inducible factor-1αLoss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition.Deletion of the Neurotrophic Factor neudesin Prevents Diet-induced Obesity by Increased Sympathetic ActivityTwo sides to every story: the HIF-dependent and HIF-independent functions of pVHL.LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 ActivityHypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?PHD3-dependent hydroxylation of HCLK2 promotes the DNA damage response.New cancer targets emerging from studies of the Von Hippel-Lindau tumor suppressor protein.Catecholamine metabolomic and secretory phenotypes in phaeochromocytoma.Function and expression of prolyl hydroxylase 3 in cancers.Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features.The role of HIF prolyl hydroxylases in tumour growth.Complex role of HIF in cancer: the known, the unknown, and the unexpected.Hypoxia inducible factor-2alpha: a critical mediator of aggressive tumor phenotypes.Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cellsHypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases.HAF : the new player in oxygen-independent HIF-1alpha degradation.Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.Hypoxia and Mucosal Inflammation.Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum.Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein
P2860
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P2860
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
description
2008 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Mai 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/05/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/05/01)
@nl
наукова стаття, опублікована в травні 2008
@uk
مقالة علمية (نشرت في مايو 2008)
@ar
name
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@ast
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@en
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@nl
type
label
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@ast
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@en
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@nl
prefLabel
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@ast
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@en
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@nl
P2093
P2860
P50
P3181
P356
P1476
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
@en
P2093
Andrew I Sutherland
Bhathiya Wijeyekoon
Dania Teixeira
Denis Gallagher
Henrik Oster
Jose Lopez-Barneo
Joseph P de Bono
Katie van Geyte
Lynn G Nicholls
Martin Schneider
P2860
P304
P3181
P356
10.1128/MCB.02041-07
P407
P50
P577
2008-03-10T00:00:00Z