C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae
about
TIN2, a new regulator of telomere length in human cellsTargeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Rap1 affects the length and heterogeneity of human telomeresThe human Rap1 protein complex and modulation of telomere lengthProgressive rearrangement of telomeric sequences added to both the ITR ends of the yeast linear pGKL plasmidHigh incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegansStructural and Functional Studies of the Rap1 C-Terminus Reveal Novel Separation-of-Function MutantsThe orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNAProteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length.A class of single-stranded telomeric DNA-binding proteins required for Rap1p localization in yeast nuclei.Multiple interactions in Sir protein recruitment by Rap1p at silencers and telomeres in yeast.A protein-counting mechanism for telomere length regulation in yeast.Isolation and characterization of two Saccharomyces cerevisiae genes that encode proteins that bind to (TG1-3)n single strand telomeric DNA in vitroThe yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiaeTel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast.Rap1 prevents telomere fusions by nonhomologous end joining.Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast.SUM1-1, a dominant suppressor of SIR mutations in Saccharomyces cerevisiae, increases transcriptional silencing at telomeres and HM mating-type loci and decreases chromosome stability.Subtelomeric proteins negatively regulate telomere elongation in budding yeast.Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae.Extra telomeres, but not internal tracts of telomeric DNA, reduce transcriptional repression at Saccharomyces telomeres.The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae.Yeast telomerase is specialized for C/A-rich RNA templates.Regulation of histone deposition proteins Asf1/Hir1 by multiple DNA damage checkpoint kinases in Saccharomyces cerevisiae.Natural and pharmacological regulation of telomeraseTetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint.Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres.Saccharomyces cerevisiae Esc2p interacts with Sir2p through a small ubiquitin-like modifier (SUMO)-binding motif and regulates transcriptionally silent chromatin in a locus-dependent manner.The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalizationTelomere-binding and Stn1p-interacting activities are required for the essential function of Saccharomyces cerevisiae Cdc13p.Repression of rRNA synthesis due to a secretory defect requires the C-terminal silencing domain of Rap1p in Saccharomyces cerevisiaeAtm inactivation results in aberrant telomere clustering during meiotic prophase.Altered telomere nuclear matrix interactions and nucleosomal periodicity in ataxia telangiectasia cells before and after ionizing radiation treatmentIn vivo analysis of functional regions within yeast Rap1p.The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis.Enhancement of telomere-plasmid segregation by the X-telomere associated sequence in Saccharomyces cerevisiae involves SIR2, SIR3, SIR4 and ABF1.Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres.Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure.
P2860
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P2860
C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@ast
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@en
type
label
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@ast
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@en
prefLabel
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@ast
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@en
P2093
P2860
P356
P1476
C-terminal truncation of RAP1 ...... on in Saccharomyces cerevisiae
@en
P2093
P2860
P304
P356
10.1128/MCB.12.11.5159
P407
P577
1992-11-01T00:00:00Z