Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
about
Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.Cryo-EM analysis of homodimeric full-length LRRK2 and LRRK1 protein complexes.Leucine-rich repeat kinase 2 and Parkinson's disease.Exosomes in Parkinson's Disease.Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease.LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson's Disease Mouse Model.Role of exosomal proteins in cancer diagnosisSelective LRRK2 kinase inhibition reduces phosphorylation of endogenous Rab10 and Rab12 in human peripheral mononuclear blood cells.Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers.A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson's Disease.LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.Achieving neuroprotection with LRRK2 kinase inhibitors in Parkinson disease.Regulation of LRRK2 by Phosphatases.LRRK2 Phosphorylation.Reduced penetrance of Leucine-rich repeat kinase 2 mutations: Discovering genetic factors of endogenous disease protection.Detection of endogenous S1292 LRRK2 autophosphorylation in mouse tissue as a readout for kinase activity.Exosomes and Stem Cells in Degenerative Disease Diagnosis and Therapy.Finding useful biomarkers for Parkinson's disease
P2860
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P2860
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
@ast
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
@en
type
label
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
@ast
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
@en
prefLabel
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
@ast
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers.
@en
P2093
P2860
P1433
P1476
Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers
@en
P2093
Kyle B Fraser
LRRK2 Cohort Consortium
Roy N Alcalay
P2860
P304
P356
10.1212/WNL.0000000000002436
P407
P577
2016-02-10T00:00:00Z