about
Normal human chromosomes have long G-rich telomeric overhangs at one endCDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanismshnRNP A2, a potential ssDNA/RNA molecular adapter at the telomereWild-derived inbred mouse strains have short telomeres.Smurf2 up-regulation activates telomere-dependent senescenceTelomere elongation in immortal human cells without detectable telomerase activityTelomere shortening and apoptosis in telomerase-inhibited human tumor cellsNot so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystalhTERT protein expression is independent of clinicopathological parameters and c-Myc protein expression in human breast cancerNew trends in molecular and cellular biomarker discovery for colorectal cancerTelomere Length and the Cancer-Atherosclerosis Trade-OffBiology of telomeres: importance in etiology of esophageal cancer and as therapeutic targetMolecular regulation of telomerase activity in agingAxis of ageing: telomeres, p53 and mitochondriaThe role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignanciesHeterochromatin formation promotes longevity and represses ribosomal RNA synthesisA novel telomerase activator suppresses lung damage in a murine model of idiopathic pulmonary fibrosisStructure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formationStructure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequenceStructure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structuresModulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae.Functional requirement of p23 and Hsp90 in telomerase complexesDNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptaseCell proliferation in the presence of telomeraseMyc activates telomeraseTelomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cellsOxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cellsHost Demise as a Beneficial Function of Indigenous Microbiota in Human HostsA highly selective telomerase inhibitor limiting human cancer cell proliferationTelomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activityTelomere length predicts replicative capacity of human fibroblastsA box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' endTelomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax.Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells.Immortalised breast epithelia survive prolonged DNA replication stress and return to cycle from a senescent-like state.Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells.Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls.Single-stranded DNA binding factor AtWHY1 modulates telomere length homeostasis in Arabidopsis.Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells.Interaction of an Arabidopsis RNA-binding protein with plant single-stranded telomeric DNA modulates telomerase activity.
P2860
Q22065787-F7593636-9BCE-4E99-9AC6-4F790D24E672Q24302257-4DEB642C-56F4-48F7-B6DE-AD530286614CQ24338517-2D298EA6-A453-4A66-A335-76935F14F3C7Q24528999-967B5F5F-D613-4D4A-80A4-694082878F9CQ24558758-AD3A92BF-1FCD-4C9D-95C4-9B52844CA514Q24598626-0FE8FE0B-A28E-4ABA-93CF-8A021DBBF76CQ24598974-093AD326-314F-439C-A275-EB42A2912C61Q24813445-C09B0E8B-1012-4E56-9EA8-1503749B31ADQ24815255-2AD17348-ED2C-4654-951B-0D240D150B7DQ26739049-0A8EAFF5-0073-4BDA-9BAA-8F6C69C4047EQ26744052-85FF9C42-F0A9-4C19-9B32-F8AC58EC13A1Q26829993-2314DC41-871E-464F-BCBA-299371ABCBFCQ26861714-83492360-54CE-4397-8F84-1F7CE51C4DEAQ26865873-FE277FBC-B2D7-4386-B170-62D6104E77C4Q27008221-7B278D5F-1E73-4916-B280-37E6B51EC444Q27334993-44B06D50-F89A-4671-89BC-C265929D12E9Q27335099-E8614721-FEF9-41BE-95F4-4F1BA103B612Q27644282-31F6179E-A28A-4174-9571-8361C1F881A5Q27646647-FAACB92D-30C1-43F9-93DF-DAC2CA6602CFQ27658371-72614C07-AB3E-4DCF-84CF-DA279BE2A5BEQ27932078-FADD177E-E95C-42D4-B005-87F48DBA4E4CQ28115669-894ECBD8-ABA2-48C3-B3EE-69AF22FF47D3Q28266367-9B484ED0-8664-4824-B98D-D1EBDC0ADF05Q28474871-61B201DE-2C36-4032-BDE5-443CDCB786B4Q28505489-FA26EEE8-0E93-401A-819A-AD4D712ECADCQ28538403-E560914B-16CF-4511-A81D-E2E00EED704EQ28544458-B48617B4-8AE9-4DD1-9C2B-ED704C800354Q29030873-BC03B125-BDCF-40FC-9DDE-E4689822B680Q29301431-68D52E30-3A87-46D7-8EE9-7D11AD9173FBQ29615388-BDE7C585-1509-4865-AE3B-08CEFC7AD2FAQ29615745-C3EBD2A6-912E-4713-B99C-8ABFAFEA6EE3Q29615761-492E96CA-6A12-4279-9653-67779416B0DFQ30472352-6FA8F5F3-4A53-4FE6-A83C-78D071358F09Q30500386-DD966226-5581-4A3F-82F6-40C00FFFB9A0Q30585968-FDAB9953-650B-48C2-A04D-6EFEBC345C37Q30771484-162F45FC-67E3-4689-94F5-F5C624ACB95AQ30801573-4E8790B6-8ECB-4CA3-BF2F-1D7B86F63A74Q31091598-44995516-D17B-4CAC-8D73-9F1BDCA86772Q31156804-A21F8011-B424-4023-8394-BDEEA451DE9DQ33196380-2A3B7F17-7408-4A3A-9F48-0C8F8A033966
P2860
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Telomere loss: mitotic clock or genetic time bomb?
@ast
Telomere loss: mitotic clock or genetic time bomb?
@en
type
label
Telomere loss: mitotic clock or genetic time bomb?
@ast
Telomere loss: mitotic clock or genetic time bomb?
@en
prefLabel
Telomere loss: mitotic clock or genetic time bomb?
@ast
Telomere loss: mitotic clock or genetic time bomb?
@en
P1433
P1476
Telomere loss: mitotic clock or genetic time bomb?
@en
P2093
P304
P356
10.1016/0921-8734(91)90018-7
P407
P577
1991-03-01T00:00:00Z