about
Menin stimulates homology-directed DNA repairSKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivationInherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversiesCrystal structure of menin reveals binding site for mixed lineage leukemia (MLL) proteinThe same pocket in menin binds both MLL and JUND but has opposite effects on transcriptionReexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouseCharacterisation of prostate cancer lesions in heterozygous Men1 mutant miceRegulation of cyclin B2 expression and cell cycle G2/m transition by meninMenin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.Trithorax group proteins: switching genes on and keeping them active.p27 Loss Is Associated with Poor Prognosis in Gastroenteropancreatic Neuroendocrine Tumors.The tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.Identification of CD34+ and CD34- leukemia-initiating cells in MLL-rearranged human acute lymphoblastic leukemiaChallenges and opportunities in targeting the menin-MLL interaction.Menin represses tumorigenesis via repressing cell proliferation.Unique gene expression profile associated with an early-onset multiple endocrine neoplasia (MEN1)-associated pituitary adenomaMolecular analysis of MEN1 expression in MCF7, T47D and MDA-MB 468 breast cancer cell lines treated with adriamycin using RT-PCR and immunocytochemistry.PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target.MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair.Menin mediates epigenetic regulation via histone H3 lysine 9 methylation.Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with 1613 literature MEN1 patients with or without pancreatic endocrine tumors.Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective.Neuroendocrine tumors and tumor syndromes in childhood.Menin is required for optimal processing of the microRNA let-7a.Multiple endocrine neoplasia type 1 (MEN1).Molecular pathogenesis of pancreatic neuroendocrine tumors.Menin localization in cell membrane compartmentMAJOR MOLECULAR GENETIC DRIVERS IN SPORADIC PRIMARY HYPERPARATHYROIDISM.Characterization of DNA damage-dependent cell cycle checkpoints in a menin-deficient model.Expression and subcellular localization of menin in human cancer cells.Translational Diagnostics and Therapeutics in Pancreatic Neuroendocrine Tumors.Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells.High incidence of mammary intraepithelial neoplasia development in Men1-disrupted murine mammary glands.Menin Modulates Mammary Epithelial Cell Numbers in Bovine Mammary Glands Through Cyclin D1.Epigenetic regulation by the menin pathway.A novel deletion of the MEN1 gene in a large family of multiple endocrine neoplasia type 1 (MEN1) with aggressive phenotype.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
In search of tumor suppressing functions of menin
@ast
In search of tumor suppressing functions of menin
@en
type
label
In search of tumor suppressing functions of menin
@ast
In search of tumor suppressing functions of menin
@en
prefLabel
In search of tumor suppressing functions of menin
@ast
In search of tumor suppressing functions of menin
@en
P2860
P1476
In search of tumor suppressing functions of menin
@en
P2093
Xianxin Hua
Yuqing Yang
P2860
P356
10.1016/J.MCE.2006.12.032
P478
P577
2007-01-11T00:00:00Z