The prion strain phenomenon: molecular basis and unprecedented features.
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Pruritus is a common feature in sheep infected with the BSE agentPrion hypothesis: the end of the controversy?Molecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseasesStructural classification of toxic amyloid oligomersFunction of SSA subfamily of Hsp70 within and across species varies widely in complementing Saccharomyces cerevisiae cell growth and prion propagation.Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.Lack of prion transmission by sexual or parental routes in experimentally infected hamstersThe prion hypothesis: from biological anomaly to basic regulatory mechanism.The intricate mechanisms of neurodegeneration in prion diseases.The glycosylation status of PrPC is a key factor in determining transmissible spongiform encephalopathy transmission between speciesStriatal pathology underlies prion infection-mediated hyperactivity in mice.Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features.Molecular pathogenesis of sporadic prion diseases in man.Strain conformation, primary structure and the propagation of the yeast prion [PSI+].Strain-dependent profile of misfolded prion protein aggregates.Post-translational changes to PrP alter transmissible spongiform encephalopathy strain properties.Cell-specific susceptibility to prion strains is a property of the intact cell.Identity determinants of infectious proteins.Cell-free propagation of prion strains.REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.Reduction of prion infectivity in packed red blood cells.Role of Prion Replication in the Strain-dependent Brain Regional Distribution of PrionsEvidence for prion-like mechanisms in several neurodegenerative diseases: potential implications for immunotherapyCrossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions.A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP.Similarities between forms of sheep scrapie and Creutzfeldt-Jakob disease are encoded by distinct prion types.Could avian scavengers translocate infectious prions to disease-free areas initiating new foci of chronic wasting disease?Laboratory activities involving transmissible spongiform encephalopathy causing agents: risk assessment and biosafety recommendations in Belgium.Cross currents in protein misfolding disorders: interactions and therapy.Polymorphism at 129 dictates metastable conformations of the human prion protein N-terminal β-sheet.Nanoimaging for prion related diseases.Fate of prions in soil: a review.Biochemical and strain properties of CJD prions: complexity versus simplicity.Nanopore analysis: An emerging technique for studying the folding and misfolding of proteins.A closer look at prion strains: characterization and important implications.Implications of prion adaptation and evolution paradigm for human neurodegenerative diseases.The transmissible spongiform encephalopathies of livestock.Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo.Pathogenic mechanisms of prion protein, amyloid-β and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers.Potential mechanisms and implications for the formation of tau oligomeric strains.
P2860
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P2860
The prion strain phenomenon: molecular basis and unprecedented features.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The prion strain phenomenon: molecular basis and unprecedented features.
@ast
The prion strain phenomenon: molecular basis and unprecedented features.
@en
type
label
The prion strain phenomenon: molecular basis and unprecedented features.
@ast
The prion strain phenomenon: molecular basis and unprecedented features.
@en
prefLabel
The prion strain phenomenon: molecular basis and unprecedented features.
@ast
The prion strain phenomenon: molecular basis and unprecedented features.
@en
P2093
P2860
P1476
The prion strain phenomenon: molecular basis and unprecedented features.
@en
P2093
Claudio Soto
Karim Abid
Rodrigo Morales
P2860
P304
P356
10.1016/J.BBADIS.2006.12.006
P407
P577
2006-12-15T00:00:00Z