Isolation, sequence and expression of a novel mouse brain cDNA, mIA-2, and its relatedness to members of the protein tyrosine phosphatase family.
about
Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetesMolecular cloning and characterization of PTP pi, a novel receptor-like protein-tyrosine phosphataseICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granulesIdentification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragmentThe neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretionβ2-Syntrophin is a Cdk5 substrate that restrains the motility of insulin secretory granulesRequirement of regulated endocrine-specific protein-18 for development and expression of regulated endocrine-specific protein-18 isoform c in miceMolecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranesThe dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion.The 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.Disruption of gene expression rhythms in mice lacking secretory vesicle proteins IA-2 and IA-2βAn islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies.IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).Expression, characterization, processing and immunogenicity of an insulin-dependent diabetes mellitus autoantigen, IA-2, in Sf-9 cells.Post-translational modifications of ICA512, a receptor tyrosine phosphatase-like protein of secretory granules.Overexpression of the autoantigen IA-2 puts beta cells into a pre-apoptotic state: autoantigen-induced, but non-autoimmune-mediated, tissue destruction.
P2860
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P2860
Isolation, sequence and expression of a novel mouse brain cDNA, mIA-2, and its relatedness to members of the protein tyrosine phosphatase family.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@ast
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@en
type
label
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@ast
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@en
prefLabel
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@ast
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@en
P2093
P356
P1476
Isolation, sequence and expres ...... n tyrosine phosphatase family.
@en
P2093
P304
P356
10.1006/BBRC.1994.2549
P407
P577
1994-10-01T00:00:00Z